Molecular electrochemical switching elements for bioimaging
| Project/Area Number |
15H05415
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nano/Microsystems
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| Research Institution | Tohoku University |
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Principal Investigator |
Ino Kosuke 東北大学, 工学研究科, 准教授 (00509739)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥24,180,000 (Direct Cost: ¥18,600,000、Indirect Cost: ¥5,580,000)
Fiscal Year 2017: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2016: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2015: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
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| Keywords | 電気化学分析 / バイオ計測 / バイオMEMS / マイクロ・ナノ化学 / 微小電極アレイ / 細胞解析 / ナノ・マイクロ化学 / バイオイメージング |
|---|
| Outline of Final Research Achievements |
This study presents the molecular electrochemical switching element based on molecular diffusion and electrochemical reaction. The element acts like a transistor. The elements were incorporated into a small chip device, and the device was characterized. The device was applied to evaluation of cell differentiation of embryonic stem cells and respiration activity of cancer cells. In addition to them, the novel electrochemical imaging system was developed using CMOS-based electrode arrays. By using the device, multiple analytes were electrochemically imaged at the same time.
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Report
(4 results)
Research Products
(51 results)
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[Journal Article] Electrochemicolor imaging using an LSI-Based device for multiplexed cell assays2017
Author(s)
Yusuke Kanno, Kosuke Ino, Hiroya Abe, Chika Sakamoto, Takehiro Onodera, Kumi Y Inoue, Atsushi Suda, Ryota Kunikata, Masahki Matsudaira, Hitoshi Shiku, Tomokazu Matsue
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Journal Title
Analytical Chemistry
Volume: 89
Issue: 23
Pages: 12778-12786
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Potentiometric bioimaging with a large-scale integration (LSI)-based electrochemical device for detection of enzyme activity2016
Author(s)
Kanno Y, Ino K, Sakamoto C, Inoue KY, Matsudaira M, Suda A, Kunikata R, Ishikawa T, Abe H, Shiku H, Matsue T
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Journal Title
Biosens. Bioelectron.
Volume: 77
Pages: 709-714
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Electrochemical imaging of dopamine release from three-dimensional-cultured PC12 cells using LSI-based amperometric sensors2015
Author(s)
Abe H, Ino K, Li CZ, Kanno Y, Inoue KY, Suda A, Kunikata R, Matsudaira M, Takahashi Y, Shiku H, Matsue T
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Journal Title
Anal. Chem.
Volume: 87
Issue: 12
Pages: 6364-6370
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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