In search for a general tendency of chordate embryonic evolution by analyzing genetic expression patterns during development
| Project/Area Number |
15H05603
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Evolutionary biology
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
Irie Naoki 東京大学, 大学院理学系研究科(理学部), 准教授 (10536121)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2017: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2016: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2015: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
|
|---|
| Keywords | 進化 / 進化発生学 / 発生 / 反復説 / 進化可能性 / EvoDevo / 発生砂時計モデル / バイオインフォマティクス |
|---|
| Outline of Final Research Achievements |
Animals, including human being, have diversified into variety of environments and changed our appearances to a great extent through evolutionary time scale. However, with unknown reasons, basic anatomical features of our body, especially for that in vertebrates (including mammals, reptiles, avian, amphibians, and fish) remained largely unchanged. By studying gene expression profiles during development, we have tackled this problem, as the developmental process is the phase that makes up our body. We have measured and analyzed tens of thousands of genes working during vertebrate embryos, and found out that re-usages of genes may have been constrained the evolutionary diversification of basic anatomical bodyplan of vertebrates.
|
Report
(4 results)
Research Products
(21 results)
-
-
-
-
-
[Journal Article] Centromere evolution and CpG methylation during vertebrate speciation2017
Author(s)
Kazuki Ichikawa, Shingo Tomioka, Yuta Suzuki, Ryohei Nakamura, Koichiro Doi, Jun Yoshimura, Masahiko Kumagai, Yusuke Inoue, Yui Uchida, Naoki Irie, Hiroyuki Takeda* & Shinich Morishita*
-
Journal Title
Nature Communications
Volume: 1833
Issue: 1
Pages: 1722-1730
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
[Journal Article] Constrained vertebrate evolution by pleiotropic genes.2017
Author(s)
Hu H, Uesaka M, Guo S, Shimai K, Lu TM, Li F, Fujimoto S, Ishikawa M, Liu S, Sasagawa Y, Zhang G, Kuratani S, Yu JK, Kusakabe TG, Khaitovich P, Irie N; EXPANDE Consortium.
-
Journal Title
Nat Ecol Evol
Volume: 1
Issue: 11
Pages: 1722-1730
DOI
Related Report
Peer Reviewed / Int'l Joint Research
-
[Journal Article] Weighted gene co-expression network analysis reveals potential genes involved in early metamorphosis process in sea cucumber Apostichopus japonicus2017
Author(s)
Yongxin Li, Mani Kikuchi, Xueyan Li, Qionghua Gao, Zijun Xiong, Yandong Ren, Ruoping Zhao, Bingyu Mao, Mariko Kondo, Naoki Irie, Wen Wang*
-
Journal Title
BBRC
Volume: 495:1
Issue: 1
Pages: 1395-1402
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-
-
