Identification of molecular mechanisms of plant iron sensing
| Project/Area Number |
15H05617
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Plant nutrition/Soil science
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| Research Institution | Ishikawa Prefectural University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2017: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
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| Keywords | 鉄欠乏 / イネ / 遺伝子発現 / 転写因子 / ユビキチンリガーゼ / センサー / センシング / 植物 / 遺伝子 / シグナル伝達 / ユビキチン |
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| Outline of Final Research Achievements |
In order to clarify intracellular iron sensors in plants, we investigated molecular mechanisms linking metal binding and regulation of iron deficiency responses in rice transcription factor IDEF1 and ubiquitin ligase HRZs. We did not observe clear changes in DNA binding property and protein stability of IDEF1 by iron nutritional conditions. In contrast, our results suggested changes in protein stability, localization and function of HRZs by their metal binding. Proteins involved in iron-sulfur cluster biosynthesis and transport, and a bZIP transcription factor, were suggested to function downstream of HRZs. Jasmonate signaling was found to be involved in early responses to iron deficiency and HRZ-based regulation of iron homeostasis in rice.
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| Academic Significance and Societal Importance of the Research Achievements |
世界の耕地の30％以上を占める石灰質土壌では、植物は鉄を吸収しにくく生育に適さないが、本研究はこのような土壌でも良好に育つ植物の開発につながる。さらに、植物が土壌中から吸収する鉄は、食物の鉄分の由来となるため、本研究は鉄栄養価の高い米などの食物の開発につながる。学術的には、植物の鉄感知を担う細胞内鉄センサーと鉄欠乏シグナルの実体は未だに明らかになっていない。本研究はこれらの解明につながる重要な知見を提供するものである。
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Report
(4 results)
Research Products
(21 results)
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[Journal Article] Jasmonate signaling is activated in the very early stages of iron deficiency responses in rice roots.2016
Author(s)
Kobayashi, T. (corresponding author), Itai, R.N., Senoura, T., Oikawa, T., Ishimaru, Y., Ueda, M., Nakanishi, H., Nishizawa, N.K.
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Journal Title
Plant Molecular Biology
Volume: 印刷中
Issue: 4-5
Pages: 533-547
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] HRZ ubiquitin ligases negatively regulate rice iron uptake, transport and accumulation under various iron conditions2017
Author(s)
Takanori Kobayashi, May Sann Aung, Reiko Nakanishi Itai, Takeshi Senoura, Hiroshi Masuda, Takaya Oikawa, Yasuhiro Ishimaru, Minoru Ueda, Hiromi Nakanishi, Naoko K. Nishizawa
Organizer
ASPB annual meeting in 2017 (Plant Biology 2017)
Related Report
Int'l Joint Research
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