| Budget Amount *help |
¥196,820,000 (Direct Cost: ¥151,400,000、Indirect Cost: ¥45,420,000)
Fiscal Year 2019: ¥39,130,000 (Direct Cost: ¥30,100,000、Indirect Cost: ¥9,030,000)
Fiscal Year 2018: ¥38,480,000 (Direct Cost: ¥29,600,000、Indirect Cost: ¥8,880,000)
Fiscal Year 2017: ¥38,740,000 (Direct Cost: ¥29,800,000、Indirect Cost: ¥8,940,000)
Fiscal Year 2016: ¥40,560,000 (Direct Cost: ¥31,200,000、Indirect Cost: ¥9,360,000)
Fiscal Year 2015: ¥39,910,000 (Direct Cost: ¥30,700,000、Indirect Cost: ¥9,210,000)
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| Outline of Final Research Achievements |
We have found for the first time that methylmercury induces brain-specific expression of TNFα. Further, although research on TNFα has been actively carried out worldwide, induction of TNFα expression via tmRT1 is not known. The results obtained by this study not only clearly explain the mechanism of methylmercury toxicity, but also lead to the creation of a new research field called: induction of TNFα expression via tmRT1.
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