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Development of High Performance Acid–Base Combined Nanocatalysts

Research Project

Project/Area Number 15H05755
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Synthetic chemistry
Research InstitutionNagoya University

Principal Investigator

Ishihara Kazuaki  名古屋大学, 工学研究科, 教授 (40221759)

Project Period (FY) 2015-05-29 – 2020-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥199,940,000 (Direct Cost: ¥153,800,000、Indirect Cost: ¥46,140,000)
Fiscal Year 2019: ¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2018: ¥39,130,000 (Direct Cost: ¥30,100,000、Indirect Cost: ¥9,030,000)
Fiscal Year 2017: ¥39,390,000 (Direct Cost: ¥30,300,000、Indirect Cost: ¥9,090,000)
Fiscal Year 2016: ¥41,210,000 (Direct Cost: ¥31,700,000、Indirect Cost: ¥9,510,000)
Fiscal Year 2015: ¥40,430,000 (Direct Cost: ¥31,100,000、Indirect Cost: ¥9,330,000)
Keywords酸塩基複合化学 / ナノ触媒 / 均一触媒 / 分子認識 / 選択性 / 超分子 / 酸 / 塩基 / 触媒 / 酸塩基複合触媒 / 不斉触媒 / ヨウ素 / 銅 / 鉄 / 触媒設計・反応 / 機能触媒 / 有機反応化学 / 有機合成化学 / プロセス化学
Outline of Final Research Achievements

High-performance supramolecular catalysts were rationally designed using non-covalent bonding interactions such as hydrogen bonding, halogen bonding, ionic interaction, resonance effect, pi-cation interaction, etc. based on acid-base combination chemistry. These nano-size catalysts were superior to small unimolecular catalysts regarding the selectivity and turn-over frequency.

Academic Significance and Societal Importance of the Research Achievements

医農薬品、香料、接着剤、塗料、液晶、有機伝導体等のファインケミカル、機能性材料の開発・合成に携わる研究者は標的化合物を合成するための最も優れた触媒を求めているのであって、必ずしも汎用性の高いレディメイド触媒を求めているわけではない。本研究課題の成果である、従来の単一分子触媒を凌駕するテーラーメイド超分子触媒は合成困難な有機化合物を短時間で効率のよい合成を可能にするため、環境低負荷型精密有機合成技術を格段に向させる。

Assessment Rating
Verification Result (Rating)

A

Assessment Rating
Result (Rating)

A+: Progress in the research exceeds the initial goal. More than expected research results are expected.

Report

(11 results)
  • 2021 Research Progress Assessment (Verification Result) ( PDF )
  • 2020 Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report   Abstract(Research Progress Assessment) ( PDF )   Research Progress Assessment (Result) ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Abstract ( PDF )   Comments on the Screening Results ( PDF )   Annual Research Report
  • Research Products

    (168 results)

All 2021 2020 2019 2018 2017 2016 2015 Other

All Int'l Joint Research (2 results) Journal Article (54 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 53 results,  Open Access: 1 results,  Acknowledgement Compliant: 6 results) Presentation (88 results) (of which Int'l Joint Research: 40 results,  Invited: 63 results) Book (6 results) Remarks (7 results) Patent(Industrial Property Rights) (2 results) Funded Workshop (9 results)

  • [Int'l Joint Research] University of California, Berekely(米国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] ICIQ(スペイン)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Synthesis of chiral organoiodine catalyst for enantioselective oxidative dearomatization reactions: N,N'-(2S,2'S)-(2-iodo-1,3-phenylene)bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide)2021

    • Author(s)
      Muhammet Uyanik, Shinichi Ishizaki, and Kazuaki Ishihara
    • Journal Title

      Organic Syntheses

      Volume: 98 Pages: 1-27

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chiral Organoiodine-catalyzed Enantioselective Oxidative Dearomatization of Phenols2021

    • Author(s)
      Muhammet Uyanik, Shinichi Ishizaki, and Kazuaki Ishihara
    • Journal Title

      Organic Syntheses

      Volume: 98 Pages: 28-50

    • DOI

      10.15227/orgsyn.098.0028

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Insight into the Mechanism of the Acylation of Alcohols with Acid Anhydrides Catalyzed by Phosphoric Acid Derivatives2021

    • Author(s)
      Hayashi Hiroyuki、Yasukochi Shotaro、Sakamoto Tatsuhiro、Hatano Manabu、Ishihara Kazuaki
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 86 Issue: 7 Pages: 5197-5212

    • DOI

      10.1021/acs.joc.1c00102

    • NAID

      120007175365

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Halogen-Bonding Interaction between I2 and N-Iodosuccinimide in Lewis Base-Catalyzed Iodolactonization2020

    • Author(s)
      Horibe Takahiro、Tsuji Yasutaka、Ishihara Kazuaki
    • Journal Title

      Organic Letters

      Volume: 22 Issue: 12 Pages: 4888-4892

    • DOI

      10.1021/acs.orglett.0c01735

    • NAID

      120006891239

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] One‐Pot Tandem Michael Addition/Enantioselective Conia‐Ene Cyclization Mediated by Chiral Iron(III)/Silver(I) Cooperative Catalysis2020

    • Author(s)
      Horibe Takahiro、Sakakibara Masato、Hiramatsu Rin、Takeda Kazuki、Ishihara Kazuaki
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 38 Pages: 16470-16474

    • DOI

      10.1002/anie.202007180

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective 1,4‐Addition Reaction of α,β‐Unsaturated Carboxylic Acids with Cycloalkanones Using Cooperative Chiral Amine-Boronic Acid Catalysts2020

    • Author(s)
      Horibe Takahiro、Hazeyama Takashi、Nakata Yuto、Takeda Kazuki、Ishihara Kazuaki
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 39 Pages: 17256-17260

    • DOI

      10.1002/anie.202007639

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemo‐ and Enantioselective Oxidative α‐Azidation of Carbonyl Compounds2020

    • Author(s)
      Uyanik Muhammet、Sahara Naoto、Tsukahara Mayuko、Hattori Yuhei、Ishihara Kazuaki
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 39 Pages: 17110-17117

    • DOI

      10.1002/anie.202007552

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantio‐ and Site‐Selective α‐Fluorination of N‐Acyl 3,5‐Dimethylpyrazoles Catalyzed by Chiral π-Cu II Complexes2020

    • Author(s)
      Ishihara Kazuaki、Nishimura Kazuki、Yamakawa Katsuya
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 59 Issue: 40 Pages: 17641-17647

    • DOI

      10.1002/anie.202007403

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hypoiodite-Catalyzed Chemoselective Tandem Oxidation of Homotryptamines to Peroxy- and Epoxytetrahydropyridoindolenines2020

    • Author(s)
      Uyanik Muhammet、Tanaka Hiroki、Ishihara Kazuaki
    • Journal Title

      Organic Letters

      Volume: 22 Issue: 20 Pages: 8049-8054

    • DOI

      10.1021/acs.orglett.0c03001

    • NAID

      120007164855

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multifactor Control of Vinyl Monomer Sequence, Molecular Weight, and Tacticity via Iterative Radical Additions and Olefin Metathesis Reactions2020

    • Author(s)
      Miyajima Masato、Satoh Kotaro、Horibe Takahiro、Ishihara Kazuaki、Kamigaito Masami
    • Journal Title

      Journal of the American Chemical Society

      Volume: 142 Issue: 44 Pages: 18955-18962

    • DOI

      10.1021/jacs.0c09289

    • NAID

      120007147364

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Aza-Friedel-Crafts Reaction of Indoles and Pyrroles Catalyzed by Chiral C1-Symmetric Bis(phosphoric Acid)2020

    • Author(s)
      Hatano Manabu、Toh Kohei、Ishihara Kazuaki
    • Journal Title

      Organic Letters

      Volume: 22 Issue: 24 Pages: 9614-9620

    • DOI

      10.1021/acs.orglett.0c03662

    • NAID

      120007164856

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] I+/TBHP Catalysis For Tandem Oxidative Cyclization To Indolo[2,3‐b]quinolines2020

    • Author(s)
      Uyanik Muhammet、Tanaka Hiroki、Ishihara Kazuaki
    • Journal Title

      Asian Journal of Organic Chemistry

      Volume: 10 Issue: 1 Pages: 164-169

    • DOI

      10.1002/ajoc.202000570

    • NAID

      120007145996

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reusable Silica‐Supported Ammonium BINSate Catalysts for Enantio‐ and Diastereoselective Friedel-Crafts‐Type Double Aminoalkylation of N‐Alkylpyrroles with Aldimines2020

    • Author(s)
      Hatano Manabu、Zhao Xue、Mochizuki Takuya、Maeda Kyogo、Motokura Ken、Ishihara Kazuaki
    • Journal Title

      Asian Journal of Organic Chemistry

      Volume: 10 Issue: 2 Pages: 360-365

    • DOI

      10.1002/ajoc.202000603

    • NAID

      120007145997

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemoselective Transesterification of Methyl (Meth)acrylates Catalyzed by Sodium(I) or Magnesium(II) Aryloxides2020

    • Author(s)
      Ng Jie Qi、Arima Hiro、Mochizuki Takuya、Toh Kohei、Matsui Kai、Ratanasak Manussada、Hasegawa Jun-Ya、Hatano Manabu、Ishihara Kazuaki
    • Journal Title

      ACS Catalysis

      Volume: 11 Issue: 1 Pages: 199-207

    • DOI

      10.1021/acscatal.0c04217

    • NAID

      120007181814

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regioselective Oxidative Chlorination of Arenols Using NaCl and Oxone2019

    • Author(s)
      Muhammet Uyanik, Naoto Sahara, and Kazuaki Ishihara
    • Journal Title

      Eur. J. Org. Chem.

      Volume: - Issue: 1 Pages: 27-31

    • DOI

      10.1002/ejoc.201801063

    • NAID

      120006623814

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Enantioselective [1,3] O-to-C Rearrangement: Dearomatization of Alkyl 2-Allyloxy/benzyloxy-1/3-naphthoates Catalyzed by a Chiral π-Cu(II) Complex2019

    • Author(s)
      Lu Yao and Kazuaki Ishihara
    • Journal Title

      Chem. Sci.

      Volume: 10 Issue: 8 Pages: 2259-2263

    • DOI

      10.1039/c8sc05601c

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ammonium Hypoiodite-catalyzed Oxidative Dearomatizative Azidation of Arenols2019

    • Author(s)
      Muhammet Uyanik, Kohei Nishioka, and Kazuaki Ishihara
    • Journal Title

      Chem. Lett.

      Volume: 48 Issue: 4 Pages: 353-356

    • DOI

      10.1246/cl.181036

    • NAID

      130007624439

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Structure and Reactivity of Aromatic Radical Cations Generated by FeCl32019

    • Author(s)
      Takahiro Horibe, Shuhei Ohmura, and Kazuaki Ishihara
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 141 Issue: 5 Pages: 1877-1881

    • DOI

      10.1021/jacs.8b12827

    • NAID

      120006643277

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ボロン酸触媒を用いるアミド縮合反応2018

    • Author(s)
      石原一彰
    • Journal Title

      PETROTECH

      Volume: 41 Pages: 16-19

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ortho-Substituent Effect on 2,4-Bis(trifluoromethyl)phenylboronic Acid-Catalyzed Dehydrative Condensation between Carboxylic Acids and Amines2018

    • Author(s)
      Ke Wang, Yanhui Lu and Kazuaki Ishihara
    • Journal Title

      Chem. Commun.

      Volume: 54 Issue: 43 Pages: 5410-5413

    • DOI

      10.1039/c8cc02558d

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Halo-oxy- and Halo-azacyclizations Induced by Chiral Amidophosphate Catalysts and Halo-Lewis Acids2018

    • Author(s)
      Yanhui Lu, Hidefumi Nakatsuji, Yukimasa Okumura, Lu Yao, and Kazuaki Ishihara
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 140 Issue: 19 Pages: 6039-6043

    • DOI

      10.1021/jacs.8b02607

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thiourea-I2 as Lewis Base-Lewis Acid Cooperative Catalysts for Iodochlorination of Alkene with In Situ-Generated I-Cl2018

    • Author(s)
      Takahiro Horibe , Yasutaka Tsuji, and Kazuaki Ishihara
    • Journal Title

      ACS Catal.

      Volume: 8 Issue: 7 Pages: 6362-6366

    • DOI

      10.1021/acscatal.8b01565

    • NAID

      120006529622

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetric Total Synthesis of (-)-Maldoxin, a Common Biosynthetic Ancestor of the Chloropupukeananin Family2018

    • Author(s)
      Takahiro Suzuki, Soichiro Watanabe, Muhammet Uyanik, Kazuaki Ishihara, Susumu Kobayashi, and Keiji Tanino
    • Journal Title

      Org. Lett.

      Volume: 20 Issue: 13 Pages: 3919-3922

    • DOI

      10.1021/acs.orglett.8b01502

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Enantioselective Aza-Friedel-Crafts Reaction of Furan with α-Ketimino Esters Induced by a Conjugated Double Hydrogen Bond Network of Chiral Bis(phosphoric Acid) Catalysts2018

    • Author(s)
      Manabu Hatano, Haruka Okamoto, Taro Kawakami, Kohei Toh, Hidefumi Nakatsuji, Akira Sakakura and Kazuaki Ishihara
    • Journal Title

      Chem. Sci.

      Volume: 9 Issue: 30 Pages: 6361-6367

    • DOI

      10.1039/c8sc02290a

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pentamethylcyclopentadienyl rhodium(III)-chiral disulfonate hybrid catalysis for enantioselective C-H bond functionalization2018

    • Author(s)
      Satake Shun、Kurihara Takumaru、Nishikawa Keisuke、Mochizuki Takuya、Hatano Manabu、Ishihara Kazuaki、Yoshino Tatsuhiko、Matsunaga Shigeki
    • Journal Title

      Nature Catalysis

      Volume: 1 Issue: 8 Pages: 585-591

    • DOI

      10.1038/s41929-018-0106-5

    • NAID

      120006709286

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chiral Pyrophosphoric Acid Catalysts for the para-Selective and Eanantioselective Aza-Friedel-Crafts Reaction of Phenols2018

    • Author(s)
      Haruka Okamoto, Kohei Toh, Takuya Mochizuki, Hidefumi Nakatsuji, Akira Sakakura, Manabu Hatano, Kazuaki Ishihara
    • Journal Title

      Synthesis

      Volume: 50 Issue: 23 Pages: 4577-4590

    • DOI

      10.1055/s-0037-1610250

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of 1,1′-Spirobiindane-7,7′-Disulfonic Acid and Disulfonimide: Application for Catalytic Asymmetric Aminalization2018

    • Author(s)
      Kurihara Takumaru、Satake Shun、Hatano Manabu、Ishihara Kazuaki、Yoshino Tatsuhiko、Matsunaga Shigeki
    • Journal Title

      Chemistry - An Asian Journal

      Volume: 13 Issue: 17 Pages: 2378-2381

    • DOI

      10.1002/asia.201800341

    • NAID

      120006716317

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chiral Supramolecular U-Shaped Catalysts Induce the Multiselective Diels-Alder Reaction of Propargyl Aldehyde2018

    • Author(s)
      Manabu Hatano, Tatsuhiro Sakamoto, Tomokazu Mizuno, Yuta Goto, and Kazuaki Ishihara
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 140 Issue: 47 Pages: 16253-16263

    • DOI

      10.1021/jacs.8b09974

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metal-free transesterification catalyzed by tetramethylammonium methyl carbonate2018

    • Author(s)
      Manabu Hatano, Yuji Tabata, Yurikai Yoshida, Kohei Toh, Kenji Yamashita, Yoshihiro Ogura, Kazuaki Ishihara
    • Journal Title

      Green Chem.

      Volume: 20 Issue: 6 Pages: 1193-1198

    • DOI

      10.1039/c7gc03858e

    • NAID

      120006486777

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Boron Tribromide‐Assisted Chiral Phosphoric Acid Catalysts for Enantioselective [2+2] Cycloaddition2018

    • Author(s)
      Tatsuhiro Sakamoto, Takuya Mochizuki, Yuta Goto, Manabu Hatano, Kazuaki Ishihara
    • Journal Title

      Chem. Asian J

      Volume: 13 Issue: 17 Pages: 2373-2377

    • DOI

      10.1002/asia.201800351

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design of High Performance Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      石原一彰
    • Journal Title

      Journal of Synthetic Organic Chemistry, Japan

      Volume: 75 Issue: 2 Pages: 98-110

    • DOI

      10.5059/yukigoseikyokaishi.75.98

    • NAID

      130005549306

    • ISSN
      0037-9980, 1883-6526
    • Related Report
      2017 Annual Research Report 2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective cycloaddition of styrenes with aldimines catalyzed by a chiral magnesium potassium binaphthyldisulfonate cluster as a chiral Broensted acid catalyst2017

    • Author(s)
      Manabu Hatano, Keisuke Nishikawa, Kazuaki Ishihara
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 139 Issue: 25 Pages: 8424-8427

    • DOI

      10.1021/jacs.7b04795

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective conjugate hydrocyanation of α,β-unsaturated N-acylpyrroles catalyzed by chiral lithium(I) phosphoryl phenoxide2017

    • Author(s)
      Manabu Hatano, Katsuya Yamakawa, Kazuaki Ishihara
    • Journal Title

      ACS Catal.

      Volume: 7 Issue: 10 Pages: 6686-6690

    • DOI

      10.1021/acscatal.7b02551

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Design of boronic acid-base complexes as reusable homogeneous catalysts in dehydrative condensations between carboxylic acids and amines2017

    • Author(s)
      Yanui Lu, Ke Wang, Kazuaki Ishihara
    • Journal Title

      Asian J. Org. Chem.

      Volume: 6 Issue: 9 Pages: 1191-1194

    • DOI

      10.1002/ajoc.201700194

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chiral hypervalent organoiodine-catalyzed enantioselective oxidative spirolactonization of naphthol derivatives2017

    • Author(s)
      Muhammet Uyanik, Takeshi Yasui, Kazuaki Ishihara
    • Journal Title

      J. Org. Chem.

      Volume: 82 Issue: 22 Pages: 11946-11953

    • DOI

      10.1021/acs.joc.7b01941

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selenium-Iodine Cooperative Catalyst for Chlorocyclization of Tryptamine Derivatives2017

    • Author(s)
      Horibe Takahiro、Ohmura Shuhei、Ishihara Kazuaki
    • Journal Title

      Organic Letters

      Volume: 19 Issue: 20 Pages: 5525-5528

    • DOI

      10.1021/acs.orglett.7b02613

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Aza-Friedel-Crafts Reaction of Indoles with Ketimines Catalyzed by Chiral Potassium Binaphthyldisulfonates2017

    • Author(s)
      Manabu Hatano, Takuya Mochizuki, Keisuke Nishikawa, Kazuaki Ishihara
    • Journal Title

      ACS Catal.

      Volume: 8 Issue: 1 Pages: 349-353

    • DOI

      10.1021/acscatal.7b03708

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ammonium hypoiodide-catalyzed peroxidative dearomatization of phenols2017

    • Author(s)
      Muhammet Uyanik, Kohei Nishioka, Kazuaki Ishihara
    • Journal Title

      Heterocycles

      Volume: 95 Issue: 2 Pages: 1132-1147

    • DOI

      10.3987/com-16-s(s)84

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 4,5-Dimethyl-2-iodoxybenzenesulfonic acid-catalyzed highly site-selective oxidation of 2-substituted phenols to 1,2-quinols2017

    • Author(s)
      Muhammet Uyanik, Tatsuya Mutsuga, Kazuaki Ishihara
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 56 Pages: 3956-3960

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective synthesis of masked benzoquinones using designer chiral hypervalent organoiodine(III) catalysis2017

    • Author(s)
      Muhammet Uyanik, Niiha Sasakura, Masahiro Mizuno, Kazuaki Ishihara
    • Journal Title

      ACS Catal.

      Volume: 7 Issue: 1 Pages: 872-876

    • DOI

      10.1021/acscatal.6b03380

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regioselective 1,4- and 1,6-conjugate additions of Grignard reagent-derived organozinc(II)ates to poly-conjugated esters2016

    • Author(s)
      Manabu Hatano, Mai Mizuno, Kazuaki Ishihara
    • Journal Title

      Org. Lett.

      Volume: 18 Issue: 18 Pages: 4462-4465

    • DOI

      10.1021/acs.orglett.6b01774

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ヨウ素触媒の開発最前線 寄稿「キラル第四級アンモニウム次亜ヨウ素酸塩触媒2016

    • Author(s)
      Muhammet Uyanik, 石原一彰
    • Journal Title

      月刊ファインケミカル

      Volume: 45 Pages: 16-24

    • Related Report
      2016 Annual Research Report
  • [Journal Article] キラルビナフチルジスルホン酸(BINSA)を用いる精密分子設計2016

    • Author(s)
      波多野学、石原一彰
    • Journal Title

      化学工業

      Volume: 67 Pages: 660-667

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Remote Tris(pentafluorophenyl)borane-Assisted Chiral Phosphoric Acid Catalysts for the Enantioselective Diels-Alder Reaction2016

    • Author(s)
      Manabu Hatano, Hideyuki Ishihara, Yuta Goto, Kazuaki Ishihara
    • Journal Title

      Synlett

      Volume: 27 Issue: 04 Pages: 564-570

    • DOI

      10.1055/s-0035-1560369

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Structurally defined molecular hypervalent iodine catalysts for intermolecular enantioselective reactions2016

    • Author(s)
      Stefan Haubenreisser, Thorsten H. Wöste, Claudio Martínez, Kazuaki Ishihara, Kilian Muñiz
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 55 Issue: 1 Pages: 413-417

    • DOI

      10.1002/anie.201507180

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Boronic Acid–DMAPO Cooperative Catalysis for Dehydrative Condensation between Carboxylic Acids and Amines2016

    • Author(s)
      Kazuaki Ishihara and Yanhui Lu
    • Journal Title

      Chem. Sci.

      Volume: 7 Issue: 2 Pages: 1276-1280

    • DOI

      10.1039/c5sc03761a

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Enantioselective Cyanosilylation of Ketones with Lithium(I) Dicyanotrimethylsilicate(IV) Catalyzed by a Chiral Lithium(I) Phosphoryl Phenoxide2016

    • Author(s)
      Manabu Hatano, Katsuya Yamakawa, Tomoaki Kawai, Takahiro Horibe, Kazuaki Ishihara
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 55 Issue: 12 Pages: 4021-4025

    • DOI

      10.1002/anie.201510682

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【特集】不斉合成の進展と最新研究: “リン酸の酸・塩基協奏機能を活用したホウ素Lewis酸-キラルリン酸複合高活性触媒の開発(Development of Highly Active Boron Lewis Acid-Assisted Chiral Phosphoric Acid Catalysts Based on the Cooperative Acid-Base Functions)”2016

    • Author(s)
      波多野学、石原一彰
    • Journal Title

      月刊ファインケミカル

      Volume: 45 Pages: 24-32

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] C- and N-Selective Grignard Addition Reactions of α-Aldimino Esters in the Presence or Absence of Zinc(II) Chloride: Synthetic Applications to Optically Active Azacycles2015

    • Author(s)
      Manabu Hatano, Kenji Yamashita, Kazuaki Ishihara
    • Journal Title

      Org. Lett.

      Volume: 17 Issue: 10 Pages: 2412-2415

    • DOI

      10.1021/acs.orglett.5b00927

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Boron Tribromide-Assisted Chiral Phosphoric Acid Catalyst for a Highly Enantioselective Diels-Alder Reaction of 1,2-Dihydropyridines2015

    • Author(s)
      Manabu Hatano, Yuta Goto, Atsuto Izumiseki, Matsujiro Akakura, Kazuaki Ishihara
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 137 Issue: 42 Pages: 13472-13475

    • DOI

      10.1021/jacs.5b08693

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Enantioselective Cyano-Alkoxycarbonylation of α-Oxoesters Promoted by Brønsted Acid–Lewis Base Cooperative Catalysts2015

    • Author(s)
      Kazuaki Ishihara* and Yoshihiro Ogura
    • Journal Title

      Organic Letters

      Volume: 17 Issue: 24 Pages: 6070-6073

    • DOI

      10.1021/acs.orglett.5b03093

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] アルキルZ 試薬:亜鉛(II)アート錯体を用いるケトン及びイミノエステルへの高効率Grignard付加反応の開発2015

    • Author(s)
      波多野学、石原一彰
    • Journal Title

      和光純薬時報

      Volume: 83 Pages: 2-5

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高機能触媒の超分子設計2015

    • Author(s)
      波多野学、石原一彰
    • Journal Title

      化学工業

      Volume: 66 Pages: 381-388

    • NAID

      40020466231

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stereoselective Electrophilic Cyclization2015

    • Author(s)
      Akira Sakakura, Kazuaki Ishihara
    • Journal Title

      The Chemical Record

      Volume: 15 Issue: 4 Pages: 728-742

    • DOI

      10.1002/tcr.201500005

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 高機能触媒設計のための新結合様式の開拓2021

    • Author(s)
      石原一彰
    • Organizer
      新春企画Zoom Webinar「新結合様式の開拓と機能の創製
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Chemoselective Transesterification of Methyl (Meth)acrylates Catalyzed by Sodium(I) or Magnesium(II) Aryloxides2021

    • Author(s)
      Jie Qi Ng, Hiro Arima, Takuya Mochizuki, Kohei Toh, Kai Matsui, Manussada Ratanasak, Jun-Ya Hasegawa, Manabu Hatano, ◯Kazuaki Ishihara
    • Organizer
      日本化学会第101春季年会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 「ヨウ素」の力2020

    • Author(s)
      石原一彰
    • Organizer
      2020 GTR Seeds Seminar(Teamsによるオンライン開催)in ITbm/GTRコンソーシアム2020年度第5回ワークショップ
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 酸塩基複合化学を基盤とする精密触媒の設計2020

    • Author(s)
      石原一彰
    • Organizer
      東亞合成株式会社R&D総合センター学術講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 酸塩基複合化学を基盤とする高機能触媒の設計2020

    • Author(s)
      石原一彰
    • Organizer
      岡山大学大学院自然科学研究科学術講演会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] The Power of Oxidative Iodine Catalysis2020

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Chiral India 2020 "New pharmaceutical technologies: Shaping the future of drug development"
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] キラルπ-銅(II)触媒を用いるアシルピラゾールのエナンチオ選択的α-ハロゲン化反応2020

    • Author(s)
      石原一彰
    • Organizer
      分子性触媒による高度分子変換技術第184委員会講習会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] U字型キラル超分し触媒を用いるプロパルギルアルデヒドのマルチ選択的Diels-Alder反応の開発2019

    • Author(s)
      波多野学、阪本竜浩、水野智一、後藤優太、石原一彰
    • Organizer
      第6回公開シンポジウム
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Rational design of high-performace catalysts based on bcid-base combination chemistry2019

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      3rd Edition of International Congress on Catalysis and Chemical Science
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 反応を自在にあやつる触媒づくりのはなし2019

    • Author(s)
      石原一彰
    • Organizer
      名古屋大学オープンレクチャー2019
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (Jiangxi Normal University)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2017 ACP Lectureship Award Lecture (Host: Prof. Ying Yeung Yeung, The Chinese University of Hong Kong)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2017 ACP Lectureship Award Lecture (Host: Prof. Hoi Lun Kwong, City University of Hong Kong)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2017 ACP Lectureship Award Lecture (Host: Ken Cham-Fai Leung, Hong Kong Baptist University)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2017 ACP Lectureship Award Lecture (Host: Prof. Ying Yeung Yeung, Chinese University of Hong Kong)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Cooperative System of Chiral Lewis Base Catalysts and Halo-Lewis Acids for Enantioselective Halocyclization2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      ISXB3 (3rd International Symposium on Halogen Bonding)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Special Organic Syntheses Lecture (Host: Prof. Scott A. Snyder)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] IBS-Catalyzed Oxidation of Alcohols2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      ICHIC 2018 (6th International Conference on Hypervalent Iodine Chemistry)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      The Mini-Symposium on Boron-catalysed Amidation: from Theory to Practice at Durham University
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Seminar (Profs. Kilian Muniz and Paolo Melchiorre)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 酸塩基複合化学を基盤とする高機能触媒の設計2018

    • Author(s)
      石原一彰
    • Organizer
      大日本住友製薬 講演会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] B(C6F5)3を触媒に用いる立体選択的Diels-Alder反応2018

    • Author(s)
      石原一彰
    • Organizer
      第11回 フルオラス科学研究会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 酸塩基複合化学を基盤とする高機能触媒の設計2018

    • Author(s)
      石原一彰
    • Organizer
      東京工業大学理工学院応用化学系 有機化学上級第五(医農薬化学)(3年生向け) ホスト:田中健教授
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 触媒をデザインして化学反応を自在に操る2018

    • Author(s)
      石原一彰
    • Organizer
      滝学園窓口 井戸康貴(進学指導主任)
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 触媒の匠工房2018

    • Author(s)
      石原一彰
    • Organizer
      テクノフェア名大2018
    • Related Report
      2018 Annual Research Report
  • [Presentation] かたちあるプロトン酸(H+)触媒を分子設計する2018

    • Author(s)
      石原一彰
    • Organizer
      テクノフェア名大2018
    • Related Report
      2018 Annual Research Report
  • [Presentation] Rational Design of Novel Chiral Polyprotic Acid Catalysts for Enantioselective Aza-Friedel-Crafts Reactions2018

    • Author(s)
      Kazuaki Ishihara, Manabu Hatano, Akira Sakakura, Haruka Okamoto, Taro Kawakami, Kohei Toh, Takuya Mochiuzki, and Hidefumi Nakatsuji
    • Organizer
      ICCEOCA-13 (The 13th International Conference on Cutting-Edge Organic Chemistry in Asia)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 分子を繋ぐ触媒をデザインする2018

    • Author(s)
      石原一彰
    • Organizer
      豊西総合大学講座
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Rational Design of High-Performance Catalysts Based on Acid-Base Combination Chemistry2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      IKCOC-14 (The 14th International Kyoto Conference on New Aspects of Organic Chemistry)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ボロン酸触媒を用いるカルボン酸の活性化2018

    • Author(s)
      石原一彰
    • Organizer
      第11回有機触媒シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Presentation] ヨウ素触媒を用いる環境低負荷型酸化反応の開発2018

    • Author(s)
      UYANIK, Muhammet(石原一彰の代理)
    • Organizer
      グリーンプロセスインキュベーションコンソーシアム(GIC)平成30年度第59回研修セミナー
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Rational Design of High-Performance Acid-Base Combined Catalysts2018

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      日本化学会春季年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (East China Normal University)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (Shanghai Jiao Tong University)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (Shanghai Institute of Materia Medica, Chinese Academy of Sciences)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts Based on Acid-Base Combination Chemistry2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (East China University of Science and Technology)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Chiral Broensted Acid Catalysts for Enantioselective Reactions2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2nd International Symposium on Precisely Deisigned Catalysts with Customized Scaffolding
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multiselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Asian Core Program Lectureship to Korea 2016 (Host: Prof. Hee-Seung Lee, KAIST (Korea Advanced Institute of Science and Technology)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Multiselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Asian Core Program Lectureship to Korea 2016 (Host: Prof. Duck-Hyung Lee, Sogang University)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Multiselective Diels-Alder Reaction Induced by Chiral Supramolecular Lewis Acid Catalysts2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Asian Core Program Lectureship to Korea 2016 (Host: Prof. Do Hyun Ryu, Sungkyunkwan University)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] エステル・アミド縮合触媒及び酸化触媒の開発2017

    • Author(s)
      石原一彰
    • Organizer
      第2回「有機分子触媒による高度分子変換技術」講習会 主催:研究開発専門委員会「有機分子触媒による高度分子変換」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Chiral Nuclophilic Amidophosphate-catalyzed Enantioselective Iodocyclization2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      18th Tetrahedron Sympsoium Asia Edition
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rational Design of Chiral Supramolecular Acid-Base Combined Catalysts2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar (Institute of Microbial Chemistry)
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ヨウ素利用の現状と将来展望2017

    • Author(s)
      石原一彰
    • Organizer
      ヨウ素学会シンポジウム市民公開講座
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] ハロゲンに魅せられて:次世代触媒の研究戦略2017

    • Author(s)
      石原一彰
    • Organizer
      あいちサイエンスフェスティバル2017「分子をつなぐキューピット!?」触媒を広げた化学の世界
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 含フッ素ボロン酸触媒を用いる脱水縮合反応によるジペプチド合成2017

    • Author(s)
      石原一彰
    • Organizer
      フルオラス科学研究会第10回シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Enantioselective Hydrocyanation of Ketones and α,β-Unsaturated N-Acylpyrroles Catalyzed by Chiral Lithium(I) Phosphoryl Phenoxide2017

    • Author(s)
      Kazuaki Ishihara, Manabu Hatano, Katsuya Yamakawa
    • Organizer
      CCEOCA-12/ARNCEOCA-3
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Tunable Chiral Broensted Acid Catalysts for Enantioselective Reactions2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Chiral India 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Chiral Nucleophilic Amidophosphate-catalyzed Enantioselective Iodocyclization2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      1st Singapore Japan Germany Trilateral Symposium on Precision Synthesis & Catalysis
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Boronic Acid-Catalyzed Dehydrative Condensation Reaction Directed towards Peptide Synthesis2017

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      The 2nd M&M SYNTHECH Unit International Meeting 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 触媒の鍵穴制御による高次選択的反応の開発2017

    • Author(s)
      石原一彰
    • Organizer
      日本化学会第97春季年会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 第四級アンモニウム円触媒を用いるエステル交換反応2016

    • Author(s)
      石原一彰
    • Organizer
      共栄社化学株式会社奈良研究所講演会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 酵素を凌駕するテーラーメイド触媒の開発を目指して2016

    • Author(s)
      石原一彰
    • Organizer
      (独)日本学術振興会創造機能化学第116委員会 東海地区講演会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 強力な研究室を作るためのマネジメント2016

    • Author(s)
      石原一彰
    • Organizer
      CSJ化学フェスタ
    • Related Report
      2016 Annual Research Report
  • [Presentation] nantioselective Addition Reactions of 3-Butynoyl-1H-pyrazole Catalyzed by Chiral π-Cu(II) Complexes2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      C&FC 2016 (Catalysis and Fine Chemicals 2016)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Enantioselective Addition Reactions of 3-Butynoyl-1H-pyrazole Catalyzed by Chiral π-Cu(II) Complexes2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Chiral India 2016 (5th International Conference and Exhibition)
    • Related Report
      2016 Annual Research Report
  • [Presentation] テーラーメイド触媒の設計2016

    • Author(s)
      石原一彰
    • Organizer
      高知大学理学部応用理学科講演会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 有機反応の立体化学を触媒で自在に制御する2016

    • Author(s)
      石原一彰
    • Organizer
      平成28年度有機合成化学協会東海支部若手研究者のためのセミナー
    • Related Report
      2016 Annual Research Report
  • [Presentation] I(III)-Catalyzed Enantioselective Synthesis of Masked ortho-Benzoquinones and Related Reactions2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      ICHIC 2016 (5th International Conference of Hypervalent Iodine Chemistry)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Enantioselective iodocyclization reacions induced by chiral Lewis acid-base catalysis2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Westfaelische Wilhelms-University Muenster Seminar
    • Related Report
      2016 Annual Research Report
  • [Presentation] Enantioselective iodocyclization reacions induced by chiral Lewis acid-base catalysi2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Ruhr University Bochum Seminar
    • Related Report
      2016 Annual Research Report
  • [Presentation] Cooperative Activation with Chiral Lewis Base Catalysts and N-Haloimides: Catalytic Enantioselective Iodocyclization2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Stockholm University Seminar
    • Related Report
      2016 Annual Research Report
  • [Presentation] Cooperative Activation with Chiral Lewis Base Catalysts and N-Haloimides: Catalytic Enantioselective Iodocyclization2016

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      2nd International Symposium on Halogen Bonding (ISXB2)
    • Related Report
      2016 Annual Research Report
  • [Presentation] フッ素置換基を利用する触媒設計2016

    • Author(s)
      石原一彰
    • Organizer
      第13回フッ素相模セミナー
    • Related Report
      2016 Annual Research Report
  • [Presentation] 有機反応を自在に操るための酸塩基複合化学2016

    • Author(s)
      石原一彰
    • Organizer
      協和発酵キリン株式会社 富士リサーチパーク 講演会
    • Related Report
      2016 Annual Research Report
  • [Presentation] 酸塩基複合化学に立脚する高機能触媒の創製2016

    • Author(s)
      石原一彰
    • Organizer
      2015年度有機合成化学協会賞(学術的)受賞講演会
    • Place of Presentation
      如水会館スターホール
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] エステル・アミド縮合触媒の開発2016

    • Author(s)
      石原一彰
    • Organizer
      第5回慶應義塾大学戦略的研究基盤形成支援事業シンポジウム 有機合成化学ー効率化と環境調和性ー
    • Place of Presentation
      慶應義塾大学矢上キャンパス、厚生棟大会議室
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] [L-15] Enantioselective halocyclizations induced by chiral base-acid cooperarive catalysis2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      HALCHEM VII (7th International Meeting on Halogen Chemistry)
    • Place of Presentation
      the Jan Dlugosz University in Czestochowa, Poland
    • Year and Date
      2015-09-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 酸塩基複合化学を鍵とするキラル金属塩触媒の設計2015

    • Author(s)
      石原一彰
    • Organizer
      有機合成夏期セミナー「明日の有機合成化学」
    • Place of Presentation
      有機合成化学協会関西支部主催, 大阪科学技術センター8F 中・小ホール
    • Year and Date
      2015-09-01
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] [C-3] Design of Supramolecular Catalysts for the Enantio-, Diastereo-, Regio-, and Substrate-Selective Diels-Alder Reaction2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      第 39回内藤コンファレス The chemistry of organocatalysts 「有機分子触媒の化学 」
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ 札幌市北区東茨戸132番地
    • Year and Date
      2015-07-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 酸塩基二重活性化を利用する高機能触媒の設計:アミド宿業反応及び不斉ヘテロ環化反応への展開2015

    • Author(s)
      石原一彰
    • Organizer
      平成27年度前期(春季)有機合成化学講習会
    • Place of Presentation
      (公社)日本薬学会長井記念館長井記念ホール(東京、渋谷)
    • Year and Date
      2015-06-15
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      The Hong Kong Polytechnic University (香港理工大學), Hong Kong, China
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      The Hong Kong Baptist University (香港浸會大學), Hong Kong, China
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      The University of Hong Kong (香港大學), Hong Kong, China
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      The Hong Kong University of Science and Technology (香港科技大學), Location: Rm 4505, 4/F (Lift 25/26) Academic Building, Hong Kong, China
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ヨウ素触媒及び反応剤を用いる高選択的有機変換反応の開発2015

    • Author(s)
      石原一彰
    • Organizer
      第18回ヨウ素学会シンポジウム
    • Place of Presentation
      千葉大学西千葉キャンパス総合校舎
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 酸塩基複合化学を鍵とする触媒活性と選択性の制御2015

    • Author(s)
      石原一彰
    • Organizer
      第9回北里化学シンポジウム
    • Place of Presentation
      北里大学白金キャンパス
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] O-3 アミド脱水縮合反応に有効なフッ素含有フェニルボロン酸触媒:新たな展開へ2015

    • Author(s)
      石原一彰、魯彦会
    • Organizer
      フルオラス科学研究会第8回シンポジウム
    • Place of Presentation
      清水テルサ(静岡市東部勤労者福祉センター)7階会議室
    • Related Report
      2015 Annual Research Report
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      National Sun Yat-sen University (國立中山大學) (Host: Prof. Mi-Ju Wu), Kaohsiung, Taiwan
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      National Taiwan Normal University (國立師範大學) (Host: Hsyueh-Liang Wu), Taipei, Taiwa
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Rational Design of Supramolecular Acid-Base Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      Organic Seminar
    • Place of Presentation
      Academia Sinica (中央研究院) (Host: Rong-Jie Chein), Taipei, Taiwan
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 大学は人生の通過点に過ぎない。その先の夢に向かって、今すべきことを。2015

    • Author(s)
      石原一彰
    • Organizer
      プチカー(大学・学部を知るワークショップ)
    • Place of Presentation
      愛知県立丹羽高等学校
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Rational Design of Chiral Acid-Base Combined Catalysts2015

    • Author(s)
      Kazuaki Ishihara
    • Organizer
      14th Symposium on Chemical Approach to Chirality
    • Place of Presentation
      Morimoto Memorial Hall, Kagurazaka, Tokyo
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Boronic acid-DMAPO cooperative catalysis for dehydrative condensation of carboxylic acids with amines2015

    • Author(s)
      Kazuaki Ishihara, Yanhui Lu
    • Organizer
      Recent Trends in Organocatalysis (#122) [1A], Mid-Pacific Center, Coral 4 (Hilton Hawaiian Village), Pacifichem 2015
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ORGN 1172: Enantioselective iodocyclization induced by chiral base-acid cooperative catalysis2015

    • Author(s)
      Kazuaki Ishihara, Hidefumi Nakatsuji
    • Organizer
      Recent Trends in Organocatalysis (#122) [1A], Mid-Pacific Center, Coral 4 (Hilton Hawaiian Village), Pacifichem 2015
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] ORGN 1728: Synthesis of 3,3'-Diaryl-1,1'-binaphthalene-2,2'-disulfonic Acids and Design of Chiral 3,3'-Ar2-BINSA Salt Catalysts2015

    • Author(s)
      Kazuaki Ishihara, Manabu Hatano, Keisuke Nishikawa
    • Organizer
      New Organosulfur Chemistry (#436) [3A], Mid-Pacific Center, Sea Pearl Suites 3 & 4 (Hilton Hawaiian Village), Pacifichem 2015
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 非共有結合性相互作用を鍵とする高機能触媒の設計2015

    • Author(s)
      石原一彰
    • Organizer
      日本薬学会関東支部第40回学術講演会「創薬イノベーションを支える最先端サイエンス」
    • Place of Presentation
      長井記念館長井記念ホール
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Book] Boron Reagents in Synthesis2016

    • Author(s)
      Manabu Hatano, Kazuaki Ishihara
    • Total Pages
      540
    • Publisher
      American Chemical Society
    • ISBN
      9780841231832
    • Related Report
      2016 Annual Research Report
  • [Book] Lewis Base Catalysis in Organic Synthesis2016

    • Author(s)
      Manabu Hatano and Kazuaki Ishihara
    • Total Pages
      1339
    • Publisher
      Wiley-VCH
    • ISBN
      9783527336180
    • Related Report
      2016 Annual Research Report
  • [Book] Asymmetric Dearomatization Reactions2016

    • Author(s)
      Muhammet Uyanik and Kazuaki Ishihara
    • Total Pages
      399
    • Publisher
      Wiley-VCH
    • ISBN
      9783527338511
    • Related Report
      2016 Annual Research Report
  • [Book] From biosynthesis to total synthesis: Strategies and tactics for natural products2016

    • Author(s)
      Kazuaki Ishihara
    • Total Pages
      561
    • Publisher
      Wiley-VCH
    • ISBN
      9781118751732
    • Related Report
      2016 Annual Research Report
  • [Book] 19.1.5 有機アルミニウム化合物(有機合成実験法ハンドブック 第2版(中井武編集代表))2015

    • Author(s)
      石原一彰
    • Total Pages
      1202
    • Publisher
      丸善出版
    • Related Report
      2015 Annual Research Report
  • [Book] Chapter 2. Alkali Metal (Li, Na, K)-based Catalysts (Sustainable Catalysis : With Non-endangered Metals, Part 1)2015

    • Author(s)
      Manabu Hatano, Kazuaki Ishihara
    • Total Pages
      816
    • Publisher
      The Royal Society of Chemistry
    • Related Report
      2015 Annual Research Report
  • [Remarks] K.ISHIHARA GROUP

    • URL

      https://www.ishihara-lab.net

    • Related Report
      2019 Annual Research Report
  • [Remarks] 日本の研究「効率的ナノ炭素材料構築のための反応機構解明 」

    • URL

      https://research-er.jp/articles/view/77222

    • Related Report
      2018 Annual Research Report
  • [Remarks] Chem-Station「100年以上未解明だった「芳香族ラジカルカチオン」の構造を解明!」

    • URL

      https://www.chem-station.com/blog/2019/03/arc.html

    • Related Report
      2018 Annual Research Report
  • [Remarks] 名古屋大学プレスリリース「効率的ナノ炭素材料構築のための反応機構解明 」

    • URL

      http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20190208_engg.pdf?fbclid=IwAR0Kld9Ga9bBEEEUKlkMcQRgfWE1oSfOOv0brddyO9uaJlkDeTeIbjz_GAE

    • Related Report
      2018 Annual Research Report
  • [Remarks] 石原一彰研究室 ー Ishihara Groyp

    • URL

      https://www.ishihara-lab.net/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 石原研究室

    • URL

      https://www.ishihara-lab.net

    • Related Report
      2015 Annual Research Report
  • [Remarks] K. Ishihara Laboratory

    • URL

      https://www.facebook.com/kishiharalab/

    • Related Report
      2015 Annual Research Report
  • [Patent(Industrial Property Rights)] アミド及びペプチドの製造方法2021

    • Inventor(s)
      石原一彰
    • Industrial Property Rights Holder
      国立大学法人東海国立大学機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-033966
    • Filing Date
      2021
    • Related Report
      2019 Annual Research Report
  • [Patent(Industrial Property Rights)] エステル交換反応応用触媒、化合物の反応方法及び化合物の製造方法2020

    • Inventor(s)
      石原一彰,足立 正
    • Industrial Property Rights Holder
      三菱ケミカル株式会社・国立大学法人東海国立大学機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-217052
    • Filing Date
      2020
    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] Organic Smeinar of Prof. Rajeev Prabhakar (University of Miami)2017

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seminar of Prof. Mukund Prahaladarao Sibi (University of North Dakota)2017

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seminar of Prof. Zhenlei Song (Sichan University)2016

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seminar of Prof. Scott E. Denmark (University of Illinois at Urbana-Champaign)2016

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seminar of Dr. ROng-Jie Chein (Institute of Chemistry, Academia Sinica)2016

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seminar of Prof. Zhu-Jun Yao (Nanjing)2016

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] The 1st M&M SYNTECH UNit International Meeting2016

    • Related Report
      2016 Annual Research Report
  • [Funded Workshop] Organic Seimar of Prof. Sarah E. Reisman (USA)2015

    • Place of Presentation
      名古屋大学
    • Related Report
      2015 Annual Research Report
  • [Funded Workshop] Organic Seimar of Prof. Stefan M. Huber (Germany)2015

    • Place of Presentation
      名古屋大学
    • Related Report
      2015 Annual Research Report

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Published: 2015-06-03   Modified: 2023-10-16  

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