| Budget Amount *help |
¥128,050,000 (Direct Cost: ¥98,500,000、Indirect Cost: ¥29,550,000)
Fiscal Year 2019: ¥25,480,000 (Direct Cost: ¥19,600,000、Indirect Cost: ¥5,880,000)
Fiscal Year 2018: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Fiscal Year 2017: ¥25,220,000 (Direct Cost: ¥19,400,000、Indirect Cost: ¥5,820,000)
Fiscal Year 2016: ¥26,390,000 (Direct Cost: ¥20,300,000、Indirect Cost: ¥6,090,000)
Fiscal Year 2015: ¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
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| Outline of Final Research Achievements |
This project is aimed for the elucidation of infection mechanisms of plant pathogenic fungi, using Colletotrichum orbiculare as a model plant-microbe system. We dissected infection process for two phases； one is pre-penetration stage and the other is post-penetration stage. In pre-penetration stage, we revealed that a cutin monomer functions as a signal molecule for infection structure development. And furthermore, we revealed that an alcohol oxidase catalyzes cutin metabolites of which function is essential for pathogenesis. In post-penetration stage, we focused mechanisms of accumulation of effectors to the interphase of plant and fungal cells, and revealed that endocytosis is involved in this process. Furthermore, we discovered a novel transcription factor involved in effector genes expression. Finally, we obtained the evidence that a fungal effector is targeting plant immune system which enables escaping immune response and full pathogenesis.
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