| Project/Area Number |
15H06185
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
Ozaki Kokoro 東京医科歯科大学, 医学部附属病院, 助教 (10754765)
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| Project Period (FY) |
2015-08-28 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 神経内科学 / ゲノム医科学 / 分子医学 / 分子遺伝学 / ゲノム |
|---|
| Outline of Final Research Achievements |
In order to find clinically important repeat sequences in human genome, I exploited a bioinformatics approach, which resulted in significantly important repeat sequences. I further developed a novel method to accurately measure the length of the
repeat sequences. For that purpose, I had to develop standard repeat libraries, which will be of use in the future studies. In addition, I tried measuring repeat lengths in a human neurodegenerative disorder. The analysis did not give a significant result. In summary, I found a repeat sequence as a possible risk factor for a human neurodegenerative disorder.
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