Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Outline of Final Research Achievements |
When I performed the surgery for malignant glioma in 2015 and 2016, I removed the part of tumors that MET-PET accumulated using navigation system. I took the 15 pieces of tumor of five patients in this study period. mRNA expression of these samples was analyzed by RNA sequence. I found the candidate of the targets of the treatment. One of them is the enzyme of metabolic pathway of Guanosine triphosphate. The inhibitor of this enzyme cause cell cycle arrest, and I am focusing on the mechanism of cell cycle arrest. I will examine the clinical application of this drug in future.
|