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Identification of novel surface marker of cardiac progenitor cells for heart regeneration therapy

Research Project

Project/Area Number 15H06370
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Cardiovascular medicine
Research InstitutionOsaka University

Principal Investigator

ISHIDA HIDEKAZU  大阪大学, 医学(系)研究科(研究院), 特任助教(常勤) (50467552)

Project Period (FY) 2015-08-28 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords心筋前駆細胞 / 次世代シーケンサー / 表面マーカー / 細胞表面マーカー / シングルセル解析
Outline of Final Research Achievements

We identified a novel cell surface marker of cardiac progenitor cells by using next generation sequencing of single cell cDNA derived from mouse embryonic heart field. We could purify the cardiac progenitor cells from mouse embryonic stem cells as well as human embryonic / induced pluripotent stem cells. This marker can be applied for the future heart regeneration therapy, such as cardiac progenitor cell transplantation therapy.

Report

(2 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )

URL: 

Published: 2015-08-26   Modified: 2017-05-10  

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