| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
We succeeded to establish iPS cells from odontogenic tumor in integration-, serum-, feeder-free condition. Though pathogenic mechanism of odontogenic tumor is unknown, neural crest cells were considered as one of the origins of odontogenic tumor. In order to establish a disease model, we examined how to induce iPSC into neural crest cells in complete serum free condition. We believe that our iPSC derived from odontogenic tumor will contribute to elucidation of the pathogenesis of odontogenic tumor and elucidation of onset mechanism.
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