Research Project
Grant-in-Aid for Research Activity Start-up
Striatum, which is one of the nuclei in basal ganglia, has an important role in sensory-motor learning. Recently, it has been reported that the task-related region shifts between the dorsolateral and the dorsomedial parts of striatum during this learning. However little is known when and how the responsible area in the striatum shifts during acquisition of associative learning. In this study, we assessed dynamic changes in patterns of the brain activation at different learning stages during an auditory discrimination task using a small-animal neuroimaging. Voxel-based statistical parametric mapping analysis revealed that the neural activities in the dorsolateral striatum increased in the middle learning phase, then turned to decrease at later learning phase. These findings suggest that the sensory-motor learning evokes dynamic shift of regional brain activation pattern within striatum.
All 2017 2016
All Presentation (4 results) (of which Int'l Joint Research: 1 results, Invited: 1 results)
