| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Outline of Final Research Achievements |
It is known that there are two distinct mechanisms in the regulation system in the brain. One is the diffusion system, which can regulate wide brain regions, and the other is the local and restricted inhibitory networks. We used the predator odor to induce innate stress responses in experimental animals.
We demonstrated that the concentration of noradrenaline, which is one of the monoamines known as diffusion system, was increased in the hippocampus, and was involved in inducing the stress responses.
On the other hand, we concluded that there were no selective inhibitory local networks to modify the innate stress responses in the olfactory bulb, which is the first region to receive the olfactory information in the brain, with the results of gene expression analyses.
|
