| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Using X ray-irradiation equipment or radioactive cesium gamma-source, the effect of low dose or low dose rate irradiation on the neuronal differentiation process was examined in the cultured cells. A transient low dose X ray-irradiation (100～500 mSv / 5 min) or a chronic gamma-irradiation under very low dose rate (200 mSv / year) slightly promoted the neuronal differentiation process. However, the chronic gamma irradiation under different low dose rate (200 mSv / 5 days) obviously suppressed the process. These results indicate that the low dose irradiation induces the opposite effect on the neuronal differentiation process depending on the dose rate. This study provides the useful information for the investigation of the effect of environmental radiation on the fetus growing with an active neuronal differentiation.
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