• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Functionality of peptide ingredients and development of new enteral nutrition products.

Research Project

Project/Area Number 15K00831
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionKyoto Prefectural University

Principal Investigator

Kuwahata Masashi  京都府立大学, 生命環境科学研究科, 教授 (30304512)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsゼラチン / 加水分解物 / 糖尿病 / 血糖値 / 膵臓ランゲルハンス島 / ゼラチン加水分解物 / 膵臓保護 / GLP-1 / ストレプトゾトシン / 糖尿病モデルラット
Outline of Final Research Achievements

The prevalence of diabetes mellitus has been steadily increasing each year. As a result, the prevalence of complications from diabetes has also increased.
Present study found that supplementation of gelatin hydrolysate (GH) attenuated an increase in blood glucose level in streptozotocin-induced diabetic rats. The detail mechanism by which GH regulates the blood glucose level in diabetic rats remains unclear. However, it appears that the repression of inflammation in pancreatic islets by GH has influenced, at least in part, the attenuation of increase in blood glucose level. GH has potential as an effective ingredient of enteral nutrition products for diabetic patients.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 2015

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (6 results)

  • [Journal Article] Urinary pH reflects dietary acid load in patients with type 2 diabetes2017

    • Author(s)
      Miki A, Kuwahata M, Fukui M.(他6名、6番目)
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 61 Issue: 1 Pages: 74-77

    • DOI

      10.3164/jcbn.16-118

    • NAID

      130006847649

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparisons of dietary intake in Japanese with non-alcoholic fatty liver disease and type 2 diabetes mellitus2016

    • Author(s)
      Kobayashi Y, Tatsumi H, Hattori M, Sugiyama H, Wada S, Kuwahata M, Tanaka S, Kanemasa K, Sumida Y, Naito Y, Fukui M, Kido Y.
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 59 Issue: 3 Pages: 215-219

    • DOI

      10.3164/jcbn.16-7

    • NAID

      130005268714

    • ISSN
      0912-0009, 1880-5086
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A simple evaluation method for the quality of dietary protein in rats using an indicator amino acid oxidation technique.2015

    • Author(s)
      Ogawa A, Kuwahata M, Kido Y.(他3名、5番目)
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 61 Pages: 123-130

    • NAID

      130005074128

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lower vegetable protein intake and higher dietary acid load associated with lower carbohydrate intake are risk factors for metabolic syndrome in patients with type 2 diabetes: Post-hoc analysis of a cross-sectional study.2015

    • Author(s)
      Iwase H, Kuwahata M, Fukui M.(他9名、5番目)
    • Journal Title

      J Diabetes Investig

      Volume: 6 Issue: 4 Pages: 465-472

    • DOI

      10.1111/jdi.12326

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 乳タンパク質をタンパク質源としたヒトでの標識アミノ酸酸化法の検討2017

    • Author(s)
      山本百希奈、桑波田雅士、木戸康博(他7名、6番目)
    • Organizer
      第64回日本栄養改善学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ヒトでの標識アミノ酸酸化法によるタンパク質の質評価の検討2017

    • Author(s)
      山本百希奈、桑波田雅士、木戸康博(他6名、8番目)
    • Organizer
      日本アミノ酸学会第11回学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ラット血漿アルブミンの酸化還元動態は食事性低栄養状態を反映する2016

    • Author(s)
      桑波田雅士、小林ゆき子、木戸康博
    • Organizer
      日本外科代謝栄養学会第53回学術集会
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-07-07
    • Related Report
      2016 Research-status Report
  • [Presentation] ラットにおけるたんぱく質代謝上限量の推定法の検討2016

    • Author(s)
      山本百希奈、小川亜紀、小林ゆき子、桑波田雅士、木戸康博
    • Organizer
      第70回日本栄養・食糧学会大会
    • Place of Presentation
      武庫川女子大学(兵庫県西宮市)
    • Year and Date
      2016-05-13
    • Related Report
      2016 Research-status Report
  • [Presentation] ラットにおけるたんぱく質代謝上限量の推定法の検討2016

    • Author(s)
      山本百希奈、桑波田雅士、木戸康博(他2名、4番目)
    • Organizer
      第70回日本栄養・食糧学会大会
    • Place of Presentation
      武庫川女子大学(神戸市)
    • Year and Date
      2016-05-13
    • Related Report
      2015 Research-status Report
  • [Presentation] 非アルコール性脂肪性肝疾患患者の食行動に関与する心理的要因の検討2016

    • Author(s)
      杉山紘基、桑波田雅士、木戸康博(他4名、4番目)
    • Organizer
      第70回日本栄養・食糧学会大会
    • Place of Presentation
      武庫川女子大学(神戸市)
    • Year and Date
      2016-05-13
    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi