Functionality of peptide ingredients and development of new enteral nutrition products.
Project/Area Number |
15K00831
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits
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Research Institution | Kyoto Prefectural University |
Principal Investigator |
Kuwahata Masashi 京都府立大学, 生命環境科学研究科, 教授 (30304512)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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Keywords | ゼラチン / 加水分解物 / 糖尿病 / 血糖値 / 膵臓ランゲルハンス島 / ゼラチン加水分解物 / 膵臓保護 / GLP-1 / ストレプトゾトシン / 糖尿病モデルラット |
Outline of Final Research Achievements |
The prevalence of diabetes mellitus has been steadily increasing each year. As a result, the prevalence of complications from diabetes has also increased. Present study found that supplementation of gelatin hydrolysate (GH) attenuated an increase in blood glucose level in streptozotocin-induced diabetic rats. The detail mechanism by which GH regulates the blood glucose level in diabetic rats remains unclear. However, it appears that the repression of inflammation in pancreatic islets by GH has influenced, at least in part, the attenuation of increase in blood glucose level. GH has potential as an effective ingredient of enteral nutrition products for diabetic patients.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Comparisons of dietary intake in Japanese with non-alcoholic fatty liver disease and type 2 diabetes mellitus2016
Author(s)
Kobayashi Y, Tatsumi H, Hattori M, Sugiyama H, Wada S, Kuwahata M, Tanaka S, Kanemasa K, Sumida Y, Naito Y, Fukui M, Kido Y.
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Journal Title
Journal of Clinical Biochemistry and Nutrition
Volume: 59
Issue: 3
Pages: 215-219
DOI
NAID
ISSN
0912-0009, 1880-5086
Related Report
Peer Reviewed / Open Access
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