Study of nutritional guidance methods with coenzyme Q10 intake considering genetic variation aimed at healthy longevity
| Project/Area Number |
15K00840
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits
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| Research Institution | Wayo Women's University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
金子 健彦 和洋女子大学, 生活科学系, 教授 (40233879)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 補酵素Q10 / 遺伝子多型 / 健康長寿 / 栄養強化食品 / 吸収 |
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| Outline of Final Research Achievements |
Coenzyme Q10 (CoQ10) is a candidate functional component expected to preserve and increase human’s health and prevent and retard aging and related diseases. In the present study, we found that fluctuation of CoQ10 intakes by dietary habits affects its serum levels. We also found that use of CoQ10 supplements or fortified foods is more reasonable than increase of CoQ10 intake through food intervention when we take CoQ10 as a functional component. Furthermore, we found that both the daily food habits and the genetic variation are involved in the degree of increase in serum CoQ10 at one year after intake of CoQ10 supplement. These results provide some clues to clarify the mechanism of intestinal absorption of CoQ10, leading to development of a CoQ10-fortified food that offer the health-promoting benefits to all the people.
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Report
(4 results)
Research Products
(21 results)
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[Journal Article] Inhibitory Effect of 13 Taxane Diterpenoids from Chinese yew (Taxus chinensis var. mairei) on the Proliferation of HeLa Cervical Cancer Cells2016
Author(s)
Li, Hai-Sheng; Gao, Yu-Huan; Liu, Li-Hong; Liu, Wei; Shi, Qing-Wen; Dong, Mei; Suzuki, Toshikazu; KIYOTA, Hiromasa
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Journal Title
Bioscience, Biotechnology, and Biochemistry
Volume: 80
Issue: 10
Pages: 1883-1886
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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