| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Coenzyme Q10 (CoQ10) is a candidate functional component expected to preserve and increase human’s health and prevent and retard aging and related diseases. In the present study, we found that fluctuation of CoQ10 intakes by dietary habits affects its serum levels. We also found that use of CoQ10 supplements or fortified foods is more reasonable than increase of CoQ10 intake through food intervention when we take CoQ10 as a functional component. Furthermore, we found that both the daily food habits and the genetic variation are involved in the degree of increase in serum CoQ10 at one year after intake of CoQ10 supplement. These results provide some clues to clarify the mechanism of intestinal absorption of CoQ10, leading to development of a CoQ10-fortified food that offer the health-promoting benefits to all the people.
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