• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effect of a rare sugar, D-allulose on postprandial lipid metabolism

Research Project

Project/Area Number 15K00855
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionSugiyama Jogakuen University

Principal Investigator

Naito Michitaka  椙山女学園大学, 生活科学部, 教授 (10198012)

Co-Investigator(Kenkyū-buntansha) 徳田 雅明  香川大学, 医学部, 教授 (10163974)
Co-Investigator(Renkei-kenkyūsha) KAGAYA Mieko  椙山女学園大学, 生活科学部, 准教授 (10131145)
Research Collaborator KUZAWA Kaori  椙山女学園大学, 生活科学部, 助手
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords希少糖 / プシコース / アルロース / 食後脂質代謝 / 食後高脂血 / 果糖 / 果糖ブドウ糖液糖 / 難消化性デキストリン / ショ糖 / 希少糖含有シロップ / 食後高血糖 / トリグリセライド / レムナント
Outline of Final Research Achievements

We aimed to suppress the exaggerating effect of fructose and high fructose syrup (HFS) on postprandial lipidemia induced by fat cream ingestion, using a rare sugar, D-allulose (also called as D-psicose). Allulose was effective in ameliorating postprandial glycemia compared with fructose and HFS. However, allulose similarly exaggerated postprandial lipidemia induced by the ingestion of fat cream compared with fructose and HFS. A commercially available rare sugar syrup (RSS) has no difference with HFS in terms of paostprandial lipidemia and glycemia. We also tested the effect of a water-soluble dietary fiber, resistant maltodextrin (RMD), but no effect. In conclusion, exaggeration and delay of postprandial lipidemia induced by fructose or HFS were not inhibited by substituting with alllulose or by adding RMD.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (27 results)

All 2018 2017 2016 2015 Other

All Journal Article (10 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 9 results,  Open Access: 7 results,  Acknowledgement Compliant: 4 results) Presentation (12 results) (of which Int'l Joint Research: 3 results,  Invited: 4 results) Book (2 results) Remarks (3 results)

  • [Journal Article] Differential effects of sucrose, fructose, and glucose on postprandial carbohydrate and lipid metabolism in young Japanese women2018

    • Author(s)
      Erika Mizutani, Sayuki Hashimoto, Hiromi Saito, Maiko Kato, Akihiro Yoshida,
    • Journal Title

      J Food Nutr Sci

      Volume: 6 Pages: 1-11

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fast food ingestion for lunch delays postprandial lipid metabolism in young women2017

    • Author(s)
      Maiko Kato, Akihiro Yoshida, Michitaka Naito
    • Journal Title

      J Food Nutr Sci

      Volume: 5 Issue: 3 Pages: 116-121

    • DOI

      10.11648/j.jfns.20170503.18

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relation of the physical conditions at birth and in infancy to the current status in the female university students aiming for a registered dietitian2017

    • Author(s)
      吉田安友子 加藤舞子 加賀谷みえ子 松谷康子 内藤通孝
    • Journal Title

      Journal for the Integrated Study of Dietary Habits

      Volume: 28 Issue: 3 Pages: 203-209

    • DOI

      10.2740/jisdh.28.3_203

    • NAID

      130006334169

    • ISSN
      1346-9770, 1881-2368
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Anti-obesity Effects of Wasabi Leaf Extract on Rats Fed a High-fat Diet are Related to Upregulation of mRNA Expression of β3-adrenergic Receptors in Interscapular Brown Adipose Tissue2016

    • Author(s)
      Tomoe Yamada-Kato, Saori Momoi, Isao Okunishi, Motoyasu Minami, Yuichi Oishi, Toshihiko Osawa, Michitaka Naito
    • Journal Title

      Food Science and Technology Research

      Volume: 22 Issue: 5 Pages: 665-671

    • DOI

      10.3136/fstr.22.665

    • NAID

      130005268260

    • ISSN
      1344-6606, 1881-3984
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] A novel quinone derived from 5-hydroxyindoleacetic acid reacts with protein: Possible participation of oxidation of serotonin and its metabolite in the development of atherosclerosis2016

    • Author(s)
      Kato, Y., Oki, K., Suga, N., Ono, S., Ishisaka, A., Miura, Y., Kanazawa, S., Naito, M., Kitamoto, N., Kettle, A. J.
    • Journal Title

      Free Radic Biol Med

      Volume: 101 Pages: 500-510

    • DOI

      10.1016/j.freeradbiomed.2016.11.023

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] ハンバーガーを食べるときに、同時にコーラを飲むとからだによくない!?2016

    • Author(s)
      内藤通孝
    • Journal Title

      生活の科学

      Volume: 38 Pages: 1-8

    • NAID

      120005991413

    • Related Report
      2015 Research-status Report
  • [Journal Article] 運動習慣のない若年女性に対する運動とココア摂取の効果に関する研究2016

    • Author(s)
      池田衣里 吉田安友子 加藤舞子 河合潤子 吉田晃浩 内藤通孝
    • Journal Title

      椙山女学園大学研究論集(自然科学篇)

      Volume: 47 Pages: 29-39

    • NAID

      120005991272

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] The Ingestion of a Fructose-Containing Beverage Combined with Fat Cream Exacerbates Postprandial Lipidemia in Young Healthy Women2015

    • Author(s)
      Hiromi Saito, Maiko Kato, Akihiro Yoshida, Michitaka Naito
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 22 Issue: 1 Pages: 85-94

    • DOI

      10.5551/jat.22681

    • NAID

      130004690940

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effects of Aerobic Exercise on Postprandial Carbohydrate and Lipoprotein Metabolism Following Cookie Ingestion in Healthy Young Women2015

    • Author(s)
      Sayuki Hashimoto, Erika Mizutani, Maiko Suzuki, Akihiro Yoshida, Michitaka Naito
    • Journal Title

      Journal of Nutritional Science and Vitaminology

      Volume: 61 Issue: 4 Pages: 299-305

    • DOI

      10.3177/jnsv.61.299

    • NAID

      130005102613

    • ISSN
      0301-4800, 1881-7742
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The ingestion of high-fructose syrup-containing cola with a hamburger delays postprandial lipid metabolism in young healthy Japanese women2015

    • Author(s)
      Hiromi Saito, Maiko Kato, Akihiro Yoshida, Michitaka Naito
    • Journal Title

      J Food Nutr Sci

      Volume: 3 Issue: 4 Pages: 139-146

    • DOI

      10.11648/j.jfns.20150304.11

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Effect of ingesting rare sugar syrup with fat on postprandial carbohydrate and lipid metabolism in young women2017

    • Author(s)
      Kaori Kuzawa, Amu Shinshi, Eri Ikeda, Akihiro Yoshida, Li Sui, Akram Hossain, Kazuyo Kamitori, Ikuko Tsukamoto, Masaaki Tokuda, Michitaka Naito
    • Organizer
      日本動脈硬化学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 糖・脂質の血中濃度日内変動に対するD-アルロース摂取の影響2017

    • Author(s)
      内藤通孝
    • Organizer
      希少糖研究会
    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Invited
  • [Presentation] Effect of ingesting a rare sugar D-allulose on postprandial carbohydrate and lipid metabolism in healthy young women2016

    • Author(s)
      Michitaka Naito
    • Organizer
      Symposium of International Society of Rare Sugars
    • Place of Presentation
      Takamatsu
    • Year and Date
      2016-11-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Study of postprandial lipoprotein metabolism in middle-aged Japanese men using an oral fat tolerance test2016

    • Author(s)
      Sayuki Hashimoto, Erika Mizutani, Akihiro Yoshida, Michitaka Naito
    • Organizer
      International Congress of Dietetics
    • Place of Presentation
      Granada, Spain
    • Year and Date
      2016-09-07
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of pre- vs. postprandial aerobic exercise on postprandial lipidemia induced by the ingestion of fructose with fat in healthy young women2016

    • Author(s)
      Chiharu Iijima, Eri Ikeda, Hiromi Saito, Akihiro Yoshida, Daisuke Manita, Yuji Hirowatari, Michitaka Naito
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
  • [Presentation] Effect of ingestion of a rare sugar D-psicose with fat on postprandial carbohydrate and lipid metabolism in young women2016

    • Author(s)
      Kaori Kuzawa, Chiharu IIjima, Eri Ikeda, Akihiro Yoshida, Li Sui, Akram Hossain, Kazuyo Kamitori, Ikuko Tsukamoto, Masaaki Tokuda, Michitaka Naito
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
  • [Presentation] Association between the intake of mono- and disaccharides and body composition or lipid profile in young healthy women2016

    • Author(s)
      Hiromi Saito, Erika Mizutani, Chiharu Iijima, Eri Ikeda, Kaori Kuzawa, Misato Kimbara, Akihiro Yoshida, Michitaka Naito
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 食後脂質代謝に対する果糖摂取の影響2016

    • Author(s)
      内藤通孝
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      東京
    • Year and Date
      2016-07-14
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 食後糖・脂質代謝に対する希少糖D-プシコースの効果について2016

    • Author(s)
      内藤通孝
    • Organizer
      第5回希少糖研究会
    • Place of Presentation
      伊丹
    • Year and Date
      2016-03-04
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Relation between dietary intake and fasting lipid profile in healthy young women2015

    • Author(s)
      Hiromi Saito, Chiharu Iijima, Eri Ikeda, Maiko Kato, Akihiro Yoshida, Michitaka Naito
    • Organizer
      The 47th Annual Scientific Meeting of the Japan Atherosclerosis Society
    • Place of Presentation
      仙台
    • Year and Date
      2015-07-10
    • Related Report
      2015 Research-status Report
  • [Presentation] Effects of previous-day aerobic exercise on postprandial lipidemia induced by the ingestion of fat with fructose in healthy young women2015

    • Author(s)
      Chiharu Iijima, Eri Ikeda, Hiromi Saito, Akihiro Yoshida, Michitaka Naito
    • Organizer
      The 47th Annual Scientific Meeting of the Japan Atherosclerosis Society
    • Place of Presentation
      仙台
    • Year and Date
      2015-07-10
    • Related Report
      2015 Research-status Report
  • [Presentation] Acute Effects of walking exercise on postprandial carbohydrate and lipoprotein metabolism following cookie ingestion in Japanese female students2015

    • Author(s)
      Sayuki Hashimoto, Erika Mizutani, Akihiro Yoshida, Michitaka Naito
    • Organizer
      12th Asian Congress of Nutrition
    • Place of Presentation
      横浜
    • Year and Date
      2015-05-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Book] テキスト健康科学 改訂第2版2017

    • Author(s)
      内藤通孝
    • Total Pages
      265
    • Publisher
      南江堂
    • ISBN
      9784524258857
    • Related Report
      2017 Annual Research Report 2016 Research-status Report
  • [Book] 解剖生理学実習の手引き ~人体の構造と機能の理解のために~ 改訂第4版2016

    • Author(s)
      内藤通孝
    • Total Pages
      62
    • Publisher
      中部日本教育文化会
    • Related Report
      2016 Research-status Report
  • [Remarks] 椙山女学園大学生活科学部管理栄養学科教員紹介

    • URL

      http://www.food.sugiyama-u.ac.jp/staffs/index.html

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
  • [Remarks] 椙山女学園大学栄養保健学研究室ブログ

    • URL

      http://nutr.food.sugiyama-u.ac.jp/blog/003/

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report
  • [Remarks] 椙山女学園大学生活科学部管理栄養学科教員紹介

    • URL

      http://nutr.food.sugiyama-u.ac.jp/staffs/index.html

    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi