Relationship between salt taste threshold and salt intake, and the influence of health guidance intervention on salt taste perception

• Project/Area Number: 15K00877
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits
• Research Institution: Showa University (2016-2018); Fukushima Medical University (2015)
• Principal Investigator: HASEGAWA Takeshi 昭和大学, 医学部, 准教授 (90349100)
• Co-Investigator(Kenkyū-buntansha): 佐々木 彰 福島県立医科大学, 公私立大学の部局等, 助手 (00749129) ; 西脇 宏樹 福島県立医科大学, 公私立大学の部局等, 助手 (20465173) ; 飯田 英和 福島県立医科大学, 公私立大学の部局等, 助手 (80749119) ; 福原 俊一 京都大学, 医学研究科, 教授 (30238505) ; 高田 俊彦 福島県立医科大学, 医学部, 講師 (60456077) ; 栗田 宜明 福島県立医科大学, 公私立大学の部局等, 准教授 (80736976) ; 脇田 貴文 関西大学, 社会学部, 教授 (60456861) ; 福間 真悟 京都大学, 医学研究科, 特定准教授 (60706703)
• Project Period (FY): 2015-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2017: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 塩分摂取量 / 塩分味覚 / 血圧 / 高齢者 / 体重増加 / 体重増加量 / 後期高齢者 / 健康行動 / 予測ツール / 尺度開発

Outline of Final Research Achievements

A cross-sectional study was conducted on 596 regional health checkup participants to examine the relationship between salt taste threshold with salt intake, and the association of estimated salt intake and body weight gain with blood pressure. We collected data on salt taste threshold test with Solsave, estimated salt intake by the Tanaka method, physical examination, and basic information by questionnaire. There was no significant relationship between salt taste threshold test with estimated salt intake in the subjects of this study. Analyses using a general linear models for 288 very elderly people (75 years or older) showed that estimated salt intake and body weight gain were associated with higher systolic blood pressure levels, body weight gain was also associated with higher diastolic blood pressure levels.

Academic Significance and Societal Importance of the Research Achievements

本研究結果から、後期高齢者における塩分摂取量、体重増加からの血圧上昇の定量的関連性が明らかになり、高血圧患者のみならず非高血圧患者の血圧上昇予防のエビデンスの一つを示した。また、塩分摂取量および体重増加抑制という生活習慣変容による、後期高齢者における血圧管理改善の可能性を示唆した。

Research Products

• [Journal Article] Salt intake and body weight correlate with higher blood pressure in the very elderly population: The Sukagawa study. (2019)
  • Author(s): Iida H, Kurita N, Takahashi S, Sasaki S, Nishiwaki H, Omae K, Yajima N, Fukuma S, Hasegawa T, Fukuhara S.The Sukagawa Study Group.
  • Journal Title: The Journal of Clinical Hypertension Volume: 印刷中
  • Peer Reviewed / Open Access
• [Presentation] The association between salt intake, body weight, and blood pressure in the very elderly: SUKAGAWA study (2017)
  • Author(s): 飯田英和
  • Organizer: ACP日本支部年次総会2017
• [Presentation] Development and validation of a clinical prediction rule for excessive salt intake among community dwelling adults (2017)
  • Author(s): Sho Sasaki
  • Organizer: 13th Asian-Pacific Congress of Hypertension
  • Int'l Joint Research