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Study of wireless temperature measurement and heating system for hyperthermia of cancer.

Research Project

Project/Area Number 15K01277
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionAkita University

Principal Investigator

Mitobe Kazutaka  秋田大学, 理工学研究科, 教授 (60282159)

Co-Investigator(Kenkyū-buntansha) 齊藤 元  秋田大学, 医学(系)研究科(研究院), 准教授 (20323149)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsハイパーサミア / 深部温度計測 / 非侵襲 / 磁束 / 誘導加熱 / ワイヤレス温度計測 / 悪性腫瘍 / 治療技術 / ハイパーサーミア / 低侵襲 / 感温磁性体 / 温度計測 / 末期癌 / QOL
Outline of Final Research Achievements

Hyperthermia is a therapy that utilizes thermal sensitivity of cancer cells and is suitable for improving quality of life for patients with advanced inoperable cancer. We have been studying low invasive hyperthermia therapy in which a temperature-sensitive magnetic material (FILCT) with a Curie point of 43 Celsius is injected into the affected part and a high-frequency magnetic field is applied from outside the body to heat only the tumor part. In this study, we developed elemental technology of deep part temperature measurement method that wirelessly detect from outside the body whether or not the affected part has reached a treatable temperature. In this study, it was clarified that FILCT located 10.0 cm from the drive coil (5.0 cm from the pickup coil) can be detected under the arrangement condition with the drive coil and the pickup coil facing each other.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (27 results)

All 2018 2017 2016 2015

All Journal Article (11 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 11 results,  Open Access: 2 results,  Acknowledgement Compliant: 5 results) Presentation (14 results) (of which Int'l Joint Research: 10 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Study of Wireless Temperature Measurement Induction Heating System using Magnetic Properties of Au-coated Ferromagnetic Implant with Low Curie Temperature2018

    • Author(s)
      安藝 史崇、Tonthat Loi、齊藤 元、吉村 昇、水戸部 一孝
    • Journal Title

      IEEJ Transactions on Fundamentals and Materials

      Volume: 138 Issue: 3 Pages: 76-83

    • DOI

      10.1541/ieejfms.138.76

    • NAID

      130006407379

    • ISSN
      0385-4205, 1347-5533
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Possibility and Challenges for Deaf-Blind Individuals to Enjoy Films in Theater2017

    • Author(s)
      SawakoNakajima, Naoyuki Okochi, Naoko Iizumi, Motohiko Tsuru, Kazutaka Mitobe, and Tetsujiro Yamagami
    • Journal Title

      Journal of Advanced Computational Intelligence and Intelligent Informatics

      Volume: 21 Issue: 2 Pages: 350-358

    • DOI

      10.20965/jaciii.2017.p0350

    • NAID

      130007520123

    • ISSN
      1343-0130, 1883-8014
    • Year and Date
      2017-03-20
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Using Finger Dexterity in Elderly and Younger People to Detect Cognitive Decline2017

    • Author(s)
      Katsuya Fujiwara, Hiroyuki Fujii, Kazutaka Mitobe
    • Journal Title

      Journal of Advanced Computational Intelligence and Intelligent Informatics

      Volume: 21 Issue: 2 Pages: 330-336

    • DOI

      10.20965/jaciii.2017.p0330

    • NAID

      130007520051

    • ISSN
      1343-0130, 1883-8014
    • Year and Date
      2017-03-20
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Position adjustment method and distance estimation method of magnetic field supply and detection unit for magnetic hyperthermia.2017

    • Author(s)
      Tonthat L, Aki F, Matsuda E, Saito H, Yoshimura N, Mitobe K
    • Journal Title

      IEEJ Transactions on Electrical and Electronic Engineering

      Volume: 12 Issue: S2 Pages: 3-9

    • DOI

      10.1002/tee.22547

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 自転車運転シミュレータを用いた高齢自転車乗員の横断行動の計測と交通事故誘発リスクの検討2017

    • Author(s)
      半田 修士,モハンマド ズルファデゥリ,松井 靖浩,及川 昌子,水戸部 一孝
    • Journal Title

      日本交通科学学会誌

      Volume: 16(2) Pages: 19-28

    • NAID

      130006692883

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 視覚遮蔽下でのペグボード課題における自発性瞬目の加齢変化2017

    • Author(s)
      中島佐和子,山近友里恵,黒木美百,佐藤満,山下和彦,正門由久,水戸部一孝
    • Journal Title

      ヒューマンインタフェース学会論文誌

      Volume: 19 ( 1 ) Pages: 29-32

    • NAID

      130007528568

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 若年者と高齢者を対象とした描画・計数作業の二重課題による評価手法の提案2017

    • Author(s)
      藤原克哉, 狩野秀典, 水戸部一孝
    • Journal Title

      ヒューマンインタフェース学会論文誌

      Volume: 19 ( 1 ) Pages: 25-29

    • NAID

      130007528566

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Accuracy Improvement of Low-Invasive Temperature Measurement for Hyperthermia Treatment Using a Ferromagnetic Implant with Low Curie Temperature2016

    • Author(s)
      Ryuhei M., Saito H., Suzuki M., Yoshimura N., Mitobe K.,
    • Journal Title

      Electronics and Communications in Japan

      Volume: 99, 3 Issue: 3 Pages: 55-62

    • DOI

      10.1002/ecj.11788

    • NAID

      210000173214

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Body Motion Artifact Reduction Method using Rotary Scanning for Accuracy Improvement of Wireless Temperature Measurement2016

    • Author(s)
      Tonthat Loi, Fumitaka Aki, Eiki Matsuda, Hajime Saito, Noboru Yoshimura, Kazutaka Mitobe
    • Journal Title

      IEEJ Transactions on Fundamentals and Materials

      Volume: 136 Issue: 8 Pages: 529-534

    • DOI

      10.1541/ieejfms.136.529

    • NAID

      130005254592

    • ISSN
      0385-4205, 1347-5533
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 老化が摘み動作時の姿勢およびエンドポイントに及ぼす影響2016

    • Author(s)
      富岡雅弘, 齋藤正親, 水戸部一孝
    • Journal Title

      日本バーチャルリアリティ学会論文誌

      Volume: 21, 2 Pages: 217-226

    • NAID

      130006832250

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Rotary Scanning Wireless Temperature Measurement Method for Hyperthermia using Ferromagnetic Implants2015

    • Author(s)
      Loi Tonthat, H., Saito, R.,Miyamoto, M.,Suzuki, N.,Yoshimura and K.,Mitobe
    • Journal Title

      IEEJ Transactions on Electrical and Electronic Engineering

      Volume: Vol.10 Issue: S1

    • DOI

      10.1002/tee.22157

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Improvement of Heating Efficiency and Magnetization Property of Ferromagnetic Implant with Low Curie Temperature for Hyperthermia using Nano-Magnetic Fluid2017

    • Author(s)
      Tonthat Loi, Yoshiyuki Yamamoto, Fumitaka Aki, Hajime Saito, Kazutaka Mitobe
    • Organizer
      the 8th International Conference on Materials Engineering for Resources
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Proposal of Improvement of Contact Force Visualization in Soldering Training VR System2017

    • Author(s)
      Katsuya FUJIWARA, Hideaki MIYAJIMA, Kazutaka MITOBE
    • Organizer
      the 8th International Conference on Materials Engineering for Resources
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Examination of the Influence on Precision of the Wireless Temperature Measurement Induction Heating System by 37℃ Constant Temperature Environment2017

    • Author(s)
      Fumitaka Aki, Tonthat Loi, Hajime Saito, Kazutaka Mitobe
    • Organizer
      The 4th International Symposium on Advanced Magnetic Materials and Applications (ISAMMA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Thermosensitive Implant for Magnetic Hyperthermia by Mixing Micromagnetic and Nanomagnetic Particles2017

    • Author(s)
      Tonthat Loi, Yoshiyuki Yamamoto, Fumitaka Aki, Hajime Saito, Kazutaka Mitobe
    • Organizer
      The 4th International Symposium on Advanced Magnetic Materials and Applications (ISAMMA)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 恒温環境下におけるワイヤレス温検知・誘導加熱システムの研究2017

    • Author(s)
      安藝 史崇,水戸部 一孝
    • Organizer
      第51回 日本生体医工学会東北支部大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] テラヘルツイメージングに適した電気泳動の前処理手法および画像処理手法の検討2017

    • Author(s)
      佐藤弘明,水戸部一孝,羽渕友則
    • Organizer
      第51回 日本生体医工学会東北支部大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Magnetic Hyperthermia Implant: A Mixture of Micro/Nano Magnetic Particles2017

    • Author(s)
      Loi Tonthat, Yoshiyuki Yamamoto, Fumitaka Aki, Hajime Saito, Kazutaka Mitobe
    • Organizer
      第51回日本生体医工学会東北支部大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Position Adjustment Method of Magnetic Field Supply and Detection Unit for Magnetic Hyperthermia using Ferromagnetic Implant2017

    • Author(s)
      Tonthat Loi, Fumitaka Aki, Hajime Saito, Kazutaka Mitobe
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of an Uchi Self-learning System for Mutsumi-ryu-style Shamisen Using VR Environment2016

    • Author(s)
      Takeshi Shibata, Kazutaka Mitobe, Takeshi Miura, Katsuya Fujiwara, Masachika Saito, Hideo Tamamoto
    • Organizer
      Computer Science, Intelligent Robotics and Applications, 9th International Conference
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-08-22
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Study on Shortening Latency in Body Motion Artifact Reduction Method for Accuracy Improvement of Wireless Temperature Measurement by using Symmetrical Multi-pickup coils2016

    • Author(s)
      Tonthat, L.,, Saito, H., Mitobe, K.
    • Organizer
      International Conference on Electrical Engineering
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2016-07-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Study of Induction Heating Approach with Wireless Temperature Measurement Technique for Hyperthermia2016

    • Author(s)
      Aki, F.,, Saito, H., Mitobe, K.
    • Organizer
      International Conference on Electrical Engineering
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2016-07-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] ハイパーサーミアのためのワイヤレス温度計測技術を用いた自動定温加熱制御システムの開発2016

    • Author(s)
      松田 瑛生, 安藝 史崇, トンタット ロイ, 齊藤 元, 水戸部 一孝
    • Organizer
      第55回日本生体医工学会大会
    • Place of Presentation
      富山,日本
    • Year and Date
      2016-04-26
    • Related Report
      2016 Research-status Report
  • [Presentation] Development of A Method for Joint Center Estimation and Simplified Hand Motion Capture2016

    • Author(s)
      Tang Rong, Saito Masachika and Mitobe Kazutaka
    • Organizer
      ASIAGRAPH 2016 Forum in Toyama
    • Place of Presentation
      Toyama Glass Art Museum
    • Year and Date
      2016-03-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Analysis of Index Finger and Thumb Moving Trajectory and Endpoint during Pinching Motion for Objects of Different Length.2016

    • Author(s)
      Masahiro Tomioka, Masachika Saito and Kazutaka Mitobe
    • Organizer
      ASIAGRAPH 2016 Forum in Toyama
    • Place of Presentation
      Toyama Glass Art Museum
    • Year and Date
      2016-03-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Patent(Industrial Property Rights)] 磁性体の位置探索システム、及び位置探索方法2017

    • Inventor(s)
      水戸部一孝
    • Industrial Property Rights Holder
      秋田大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] ハイパーサーミア用インプラント2017

    • Inventor(s)
      水戸部一孝
    • Industrial Property Rights Holder
      秋田大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Related Report
      2017 Annual Research Report

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Published: 2015-04-16   Modified: 2019-12-27  

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