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Development of multiscale analysis of biosignal time series

Research Project

Project/Area Number 15K01285
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionOsaka University

Principal Investigator

Kiyono Ken  大阪大学, 基礎工学研究科, 教授 (40434071)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords多重スケール解析 / 生体信号解析 / 心拍変動 / フラクタル解析 / スケーリング解析 / 長時間相互 / 長時間相関 / フラクタル / 非ガウス過程
Outline of Final Research Achievements

To analyze biosignal time series, fundamental theory and practical analysis methodology of the multiscale analysis were developed. As an important application of multiscale analysis methods, the long-range correlation analysis has been widely used. In this study, we developed a unified theory of detrending-operation-based random-walk analysis characterizing the long-range correlation observed in biosignal time series. As a practical detrending-operation, we established properties of Savitzky-Golay filter and developed a fast algorithm of the detrending-operation-based random-walk analysis using Savitzky-Golay filter. Moreover, as an application of the multiscale analysis to heart rate variability, we demonstrated that the multiscale analysis is applicable to cerebral infarction risk assessment and mortality risk assessment of cardiac patients.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (29 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (4 results) Journal Article (8 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 8 results,  Open Access: 3 results,  Acknowledgement Compliant: 7 results) Presentation (17 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Int'l Joint Research] Politecnico di Torino(イタリア)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Ecole Normale Superieure de Lyon(フランス)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Ecole Normale Superieure de Lyon(フランス)

    • Related Report
      2015 Research-status Report
  • [Int'l Joint Research] Politecnico di Torino(イタリア)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Association between Multiscale Entropy Characteristics of Heart Rate Variability and Ischemic Stroke Risk in Patients with Permanent Atrial Fibrillation2017

    • Author(s)
      Matsuoka Ryo、Yoshino Kohzoh、Watanabe Eiichi、Kiyono Ken
    • Journal Title

      Entropy

      Volume: 19 Issue: 12 Pages: 672-672

    • DOI

      10.3390/e19120672

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fast algorithm for scaling analysis with higher-order detrending moving average method2016

    • Author(s)
      Yutaka Tsujimoto, Yuki Miki, Satoshi Shimatani, Ken Kiyono
    • Journal Title

      Physical Review E

      Volume: 93 Issue: 5 Pages: 053304-053304

    • DOI

      10.1103/physreve.93.053304

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detrending moving average algorithm: Frequency response and scaling performances2016

    • Author(s)
      Anna Carbone, Ken Kiyono
    • Journal Title

      Physical Review E

      Volume: 93 Issue: 6 Pages: 063309-063309

    • DOI

      10.1103/physreve.93.063309

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Time and frequency domain characteristics of detrending-operation-based scaling analysis: Exact DFA and DMA frequency responses2016

    • Author(s)
      Ken Kiyono, Yutaka Tsujimoto
    • Journal Title

      Physical Review E

      Volume: 94 Issue: 1 Pages: 012111-012111

    • DOI

      10.1103/physreve.94.012111

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Nonlinear filtering properties of detrended fluctuation analysis2016

    • Author(s)
      Ken Kiyono, Yutaka Tsujimoto
    • Journal Title

      Physica A

      Volume: 462 Pages: 807-815

    • DOI

      10.1016/j.physa.2016.06.129

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Multiscale Analysis of Intensive Longitudinal Biomedical Signals and Its Clinical Applications2016

    • Author(s)
      T. Nakamura, K. Kiyono, H. Wendt, P. Abry, Y. Yamamoto
    • Journal Title

      Proceedings of the IEEE

      Volume: 104 Issue: 2 Pages: 242-261

    • DOI

      10.1109/jproc.2015.2491979

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Establishing a direct connection between detrended fluctuation analysis and Fourier analysis2015

    • Author(s)
      Ken Kiyono
    • Journal Title

      Physical Review E

      Volume: 92 Issue: 4 Pages: 042925-042925

    • DOI

      10.1103/physreve.92.042925

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Multiscale Entropy of the Heart Rate Variability for the Prediction of an Ischemic Stroke in Patients with Permanent Atrial Fibrillation2015

    • Author(s)
      Eiichi Watanabe, Ken Kiyono, Junichiro Hayano, Yoshiharu Yamamoto, Joji Inamasu, Mayumi Yamamoto, Tomohide Ichikawa, Yoshihiro Sobue, Masehide Harada, Yukio Ozaki
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 9 Pages: e0137144-e0137144

    • DOI

      10.1371/journal.pone.0137144

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 機械学習による心不全予後予測能の向上2018

    • Author(s)
      越川真行, 本池雄二, 市川智英, 川合真由美, 原田将英, 渡邉英一, 尾崎行男, 清野健, 島谷哲史
    • Organizer
      日本ホルター・ ノンインベイシブ 心電学研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 多重スケールSavitzky‐Golayフィルタを用いた生体信号の波形形状解析2018

    • Author(s)
      藤田壌, 清野健
    • Organizer
      計測自動制御学会関西支部・システム制御情報学会若手研究発表会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Theory and applications of detrending-operation-based fractal-scaling analysis2017

    • Author(s)
      Ken Kiyono
    • Organizer
      2017 International Conference on Noise and Fluctuations (ICNF)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Savitzky-Golay filter-based detrended fluctuation analysis: theory and its application to physiological time-series2016

    • Author(s)
      Yutaka Tsujimoto, Yasuyuki Suzuki, Masanori Shimono, Taishin Nomura, Ken Kiyono
    • Organizer
      8th International Workshop on Biosignal Interpretation
    • Place of Presentation
      大阪国際交流センター (大阪府・大阪市)
    • Year and Date
      2016-11-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Nonlinearity of heart rate variability induced by respiratory modulation2016

    • Author(s)
      Yuki Miki, Yasuyuki Suzuki, Masanori Shimono, Eiichi Watanabe, Junichiro Hayano, Yoshiharu Yamamoto, Taishin Nomura, Ken Kiyono
    • Organizer
      8th International Workshop on Biosignal Interpretation
    • Place of Presentation
      大阪国際交流センター (大阪府・大阪市)
    • Year and Date
      2016-11-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Scattering Transform of Heart Rate Variability for the Prediction of Ischemic Stroke in Patients with Atrial Fibrillation2016

    • Author(s)
      Roberto Leonarduzzi, Patrice Abry, Herwig Wendt, Ken Kiyono, Yoshiharu Yamamoto, Eiichi Watanabe, Junichiro Hayano
    • Organizer
      8th International Workshop on Biosignal Interpretation
    • Place of Presentation
      大阪国際交流センター (大阪府・大阪市)
    • Year and Date
      2016-11-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Long-range correlations in amplitude variability of HF and LF components of heart rate variability2016

    • Author(s)
      Yuki Miki, Yasuyuki Suzuki, Eiichi Watanabe, Junichiro Hayano, Yoshiharu Yamamoto, Taishin Nomura, Ken Kiyono
    • Organizer
      38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Place of Presentation
      フロリダ (アメリカ)
    • Year and Date
      2016-08-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 心拍変動の高周波数及び低周波数成分の振幅変調にみられる長時間相関2015

    • Author(s)
      三木裕貴, 鈴木康之, 野村泰伸, 渡邉英一, 早野順一郎, 山本義春, 清野健
    • Organizer
      第31回心電情報処理ワークショップ
    • Place of Presentation
      名古屋クラウンホテル(愛知県名古屋市)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 多重回帰分析による心臓植え込み型デバイスの需要推移予測2015

    • Author(s)
      島谷哲史, 渡邉英一, 鈴木康之, 野村泰伸, 清野健
    • Organizer
      第31回心電情報処理ワークショップ
    • Place of Presentation
      名古屋クラウンホテル(愛知県名古屋市)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 慢性心房細動の心拍変動特性と予後との関係2015

    • Author(s)
      清野健,渡邉英一
    • Organizer
      第31回心電情報処理ワークショップ
    • Place of Presentation
      名古屋クラウンホテル(愛知県名古屋市)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] Multiscale non-Gaussian analysis based on Mellin transform: application to heart rate variability analysis2015

    • Author(s)
      Ken Kiyono
    • Organizer
      Challenges in Data Science: a complex systems perspective
    • Place of Presentation
      Castello del Valentino, Torino, Italy
    • Year and Date
      2015-10-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 心不全患者の予後予測因子としての心拍変動低周波成分の変調特性2015

    • Author(s)
      藤井翔太, 鈴木康之, 野村泰伸, 渡邉英一, 早野順一郎, 山本義春, 清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 心拍変動の時間相関に見られるスケーリングとクロスオーバー特性2015

    • Author(s)
      三木裕貴, 鈴木康之, 野村泰伸, 渡邉英一, 早野順一郎, 山本義春, 清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 睡眠時無呼吸症候群を合併した心疾患患者における終夜睡眠ポリグラフデータの特性と予後との関係2015

    • Author(s)
      松井翔二郎, 渡邉英一, 鈴木康之, 野村泰伸, 清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 心臓植込み型デバイスの国内手術件数分析に基づく将来需要予測モデルの構築2015

    • Author(s)
      島谷哲史, 渡邉英一, 鈴木康之, 野村泰伸, 清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 心拍変動に見られる分散不均一構造の解析2015

    • Author(s)
      森脇康貴, 鈴木康之, 野村泰伸, 渡邉英一, 早野順一郎, 山本義春, 清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report
  • [Presentation] 心拍変動の非線形特性2015

    • Author(s)
      清野健
    • Organizer
      第54回日本生体医工学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-05-07
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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