Skin tissue bud formation by in vitro self-organization approach
Project/Area Number |
15K01303
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Biomedical engineering/Biomaterial science and engineering
|
Research Institution | Okayama University of Science |
Principal Investigator |
Kataoka Ken 岡山理科大学, 理学部, 教授 (10293317)
|
Co-Investigator(Kenkyū-buntansha) |
辻極 秀次 岡山理科大学, 理学部, 教授 (70335628)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
|
Keywords | 附属器原基 / 培養皮膚 / 培養皮膚組織 / 附属器 / 組織原基 / 組織形成 |
Outline of Final Research Achievements |
Human mesenchymal stem cells, human endothelial cells, mouse skin dermal cells and epidermal cells were cultured with/without mouse macrophages on Matrigel-coated culture plates in vitro. Inoculated cells were aggregated and formed spheroids with layers. When the spheroids were transplanted on the back of immune-deficient mice, very few fair follicles were observed at the transplantation site.
|
Report
(4 results)
Research Products
(16 results)
-
-
-
[Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene.2017
Author(s)
Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, and Sakaguchi M.
-
Journal Title
Oncol. Lett.
Volume: 14
Issue: 1
Pages: 1041-1048
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
-
-
-
-