Impact evaluation of magnetic fields toward a target chemotherapy
Project/Area Number |
15K01328
|
Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical systems
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Research Institution | Kanazawa University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
山田 外史 金沢大学, 環日本海域環境研究センター, 連携研究員 (80019786)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 交流磁場 / がん細胞 / 薬剤作用 / 薬剤効果 |
Outline of Final Research Achievements |
We have constructed a magnetic fields exposure system for long-term experiments with human cells, and investigated the time dependence of magnetic fields exposure influence on drug potency. The results indicated that the potency of anticancer drug, cisplatin to human lung cancer cells was increased significantly by exposure to magnetic fields for 0.5 ~4 h, not for 24 h or more. Furthermore, our results suggested that the magnetic fields enhance the potency of anticancer drugs to not only lung cancer cells but also human hepatoma cells.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Cell concentration, viability and culture composition of airborne bacteria during a dust event in Beijing,2016
Author(s)
Yuan H, Zhang D, Shi Y, Li B, Yang J, Yu X, Chen N, Kakikawa M,
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Journal Title
Journal of Environmental Sciences
Volume: -
Pages: 33-40
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Vertical distribution of airborne bacterial communities in an Asian dust downwind area, Noto Peninsula2015
Author(s)
Maki T., Hara K., Kobayashi F., Kurosaki Y., Kakikawa M., Matsuki A., Chen B., Shi G., Hasegawa H., Iwasaka Y.
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Journal Title
Atmospheric Environment
Volume: 119
Pages: 282-293
DOI
NAID
Related Report
Peer Reviewed / Int'l Joint Research
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