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Development of ultrasonic device for percutaneous epidural lysis of adhesions

Research Project

Project/Area Number 15K01340
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionTokyo University of Technology

Principal Investigator

NAEMURA Kiyoshi  東京工科大学, 医療保健学部, 准教授 (90302752)

Co-Investigator(Kenkyū-buntansha) 森田 剛  東京大学, 大学院新領域創成科学研究科, 准教授 (60344735)
Co-Investigator(Renkei-kenkyūsha) MURAMATSU Hiroshi  東京工科大学, 応用生物学部, 教授 (20373045)
Research Collaborator SAWASHIMA Moeka  東京工科大学, 応用生物学部
YOKOZAWA Hiroki  東京大学, 大学院新領域創成科学研究科
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords超音波振動子 / Raczカテーテル / ペインクリニック / 穿刺反力 / 温度分布 / ランジュバン振動子 / 反力 / 超音波振動 / ガイドワイヤ / 圧電素子 / 振動速度 / キャビテーション
Outline of Final Research Achievements

Epidural adhesions cause chronic pain. To rescue from pain, percutaneous epidural lysis of adhesions with Racz catheter has conducted in recent years. Rigid adhesions cannot resolve only by injection of hyaluronidase through the Racz catheter. In order to develop a new methodology, current research is a feasibility study for adding ultrasonic vibration to the tip of the Racz catheter. Racz catheter cut from the tip was fixed to the Langevin-type ultrasonic vibrator as a prototype. A styrene foam block was employed as specimen of substitute for adhesion. The prototype fixed with a load cell were moved linearly against the specimen. Temperature near the insertion point was measured by a thermography. As results, insertion force decreased up to 40% owing to the ultrasonic vibration, while temperature increased only 2 degrees Celsius.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (8 results)

All 2017 2016

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results) Presentation (6 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Dynamic control of the resonant frequency of ultrasonic transducer2017

    • Author(s)
      Yokozawa Hiroki、Twiefel Jens、Weinstein Michael、Hosaka Hiroshi、Morita Takeshi
    • Journal Title

      Sensors and Actuators A: Physical

      Volume: 262 Pages: 64-67

    • DOI

      10.1016/j.sna.2017.04.052

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dynamic resonant frequency control of the ultrasonic transducer for stabilizing the resonant state in wide frequency band2017

    • Author(s)
      Hiroki Yokozawa, Jens Twiefel, Michael Weinstein, Takeshi Morita
    • Journal Title

      Jpn. J. Appl. Phys

      Volume: 印刷中

    • NAID

      210000148058

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 癒着剥離のための超音波デバイスによる組織への影響の定量的評価2017

    • Author(s)
      澤嶋萌香、苗村潔、村松宏
    • Organizer
      日本機械学会 第29回バイオエンジニアリング講演会
    • Place of Presentation
      愛知県 名古屋市 ウインクあいち
    • Year and Date
      2017-01-20
    • Related Report
      2016 Research-status Report
  • [Presentation] 硬膜外神経形成術用ワイヤ型超音波デバイスの基礎研究~ Raczカテーテルへの超音波振動による癒着剥離機構付加2017

    • Author(s)
      苗村潔,澤嶋萌香,村松宏,森田剛
    • Organizer
      第26回日本コンピュータ外科学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Ultrasonic vibration of the Racz catheter’s tip for adhesiolysis2017

    • Author(s)
      K. Naemura, H. Muramatsu, T. Morita
    • Organizer
      13th Asian Conference on Computer Aided Surgery
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Resonant Frequency Tunable Langevin Transducer2017

    • Author(s)
      Takeshi Morita, Hiroki Yokozawa, Michael Weinstein and Jens Twiefel
    • Organizer
      International Conference on Advanced Electromaterials 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 超音波トロッカーの貫通性能の研究2016

    • Author(s)
      土生倖也,森田剛,苗村潔
    • Organizer
      ライフサポート学会第25回フロンティア講演会
    • Place of Presentation
      東京工科大学(東京都大田区)
    • Year and Date
      2016-03-09
    • Related Report
      2015 Research-status Report
  • [Presentation] 超音波振動子によるキャビテーションと損傷に関する研究2016

    • Author(s)
      森田康貴,森田剛,苗村潔
    • Organizer
      ライフサポート学会第25回フロンティア講演会
    • Place of Presentation
      東京工科大学(東京都大田区)
    • Year and Date
      2016-03-08
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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