| Project/Area Number |
15K01371
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagasaki University |
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Principal Investigator |
ORIGUCHI Tomoki 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (90295105)
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| Co-Investigator(Kenkyū-buntansha) |
川尻 真也 長崎大学, 医歯薬学総合研究科(医学系), 講師 (20457576)
沖田 実 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (50244091)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | リハビリテーション / 関節リウマチ / 生物学的製剤 / 関節超音波検査 / リウマチ体操 / 関節可動域 / 運動療法 / 筋力 |
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| Outline of Final Research Achievements |
Exercise therapy, joint range of motion training and gymnastics were performed in rehabilitation of rheumatoid arthritis patients receiving biologics. The exercise therapy improved powers of grip, pinch and lower extremities. Serum IL-6 concentration might be useful for the assessment of the exercise therapy. Joint ranges of motion training improved the joint ranges without no change of disease activities. Furthermore, combination with biologics and gymnastics improved the disease activities and muscle powers. Substance P concentration might be useful for the assessment of the pain. Joint sonography was useful for evaluating that rehabilitation was performed safely.
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