| Project/Area Number |
15K01414
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
松島 佳苗 京都大学, 医学研究科, 助教 (60711538)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 自閉スペクトラム症 / 感覚 / 自律神経 / 副交感神経 / 自閉症スペクトラム障害 / 感覚処理障害 |
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| Outline of Final Research Achievements |
We examined cardiac vagus nerve activity during sensory tasks involving self-produced and externally produced stimuli in children(ages 5-12 years) with autism (ASD) to investigate whether stimulus predictability affects their emotional state.We recorded electrocardiograms in 37 children with ASD and 37 typically developing(TD) children and quantified the high-frequency component of heart rate variability (HF-HRV).The recordings were performed during the resting state, self/others-tactile tasks,and self/random-auditory tasks. The ASD group had significantly lower HF-HRV than the TD group did under all recording conditions.The HF-HRV responses to self-produced and externally produced stimuli did not significantly differ for either sensory task in either group.The ASD group showed significantly higher HF-HRV during the others-tactile task than during the resting state,whereas the TD group showed significantly lower HF-HRV during the others-tactile task than during the resting state.
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