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Investigation of characteristics of age-related changes in muscle quality using spatial frequency analysis of ultrasound images

Research Project

Project/Area Number 15K01469
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionSaitama Prefectural University

Principal Investigator

Nishihara Ken  埼玉県立大学, 保健医療福祉学部, 教授 (80336495)

Co-Investigator(Kenkyū-buntansha) 河合 恒  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (50339727)
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords超音波画像 / 高齢者 / 運動機能 / 筋厚 / 筋質 / 地域在住高齢者 / 大腿四頭筋
Outline of Final Research Achievements

Muscle thickness (MT) and echo intensity can be observed from the ultrasound images of skeletal muscles. The motor functions (MFs) were measured and the ultrasound images were taken in healthy elderly and young individuals. The MTs of the lower limbs were investigated, and the echo intensities were calculated to evaluate muscle quality. As a result, the elderly individuals had less MT, and greater echo intensities were shown in the elderly individuals. Specific muscles within the measured muscles could mainly account for the decrease of MTs or increase of echo intensities. Next, the MTs of femurs were measured by ultrasound image, and MF were tested for community-dwelling elderly individuals. The MTs were significantly correlated with the MF indexes. The MTs were shown to differ in the features of the decreasing levels of the measured muscles and the correlations with the MFs.
These studies would be useful for the maintenance or improvement of MF with aging.

Academic Significance and Societal Importance of the Research Achievements

本研究の学術的意義や社会的意義は、加齢や運動不足による体表組織の変化を超音波診断画像から、筋組織と運動機能や生活機能、疾患との関連性を横断的に検討することである。大規模の地域在住高齢者の年齢による運動機能や生活機能との関係を網羅的に分析することで、サルコペニア肥満の評価や予防、介護予防、転倒予防、および生活習慣病予防に役立てることができたと考えられる。加齢による筋肉の変化の特徴や筋の脂肪沈着状態を評価し、その運動機能や生活機能低下への影響を明らかにすることができた。本研究で用いた超音波診断装置は手軽なものであり、地域住民を対象とした測定会や診察室での検査などにおいて広く実施可能である。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 5 results,  Open Access: 2 results) Presentation (4 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] Correlation of physical function with the thickness of multiple muscles of the quadriceps femoris in community-dwelling elderly individuals2018

    • Author(s)
      Nishihara Ken、Kawai Hisashi、Kera Takeshi、Hirano Hirohiko、Watanabe Yutaka、Fujiwara Yoshinori、Ihara Kazushige、Kim Hunkyung、Tanaka Masashi、Obuchi Shuichi
    • Journal Title

      Clinical Interventions in Aging

      Volume: Volume 13 Pages: 1945-1951

    • DOI

      10.2147/cia.s177237

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between statin use and physical function among community-dwelling older Japanese adults2017

    • Author(s)
      Kawai Hisashi、Ihara Kazushige、Kera Takeshi、Hirano Hirohiko、Fujiwara Yoshinori、Tanaka Masashi、Kojima Motonaga、Obuchi Shuichi
    • Journal Title

      Geriatrics & Gerontology International

      Volume: 18 Issue: 4 Pages: 623-630

    • DOI

      10.1111/ggi.13228

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Morphological and qualitative characteristics of the quadriceps muscle of community-dwelling older adults based on ultrasound imaging: classification using latent class analysis2017

    • Author(s)
      Kawai Hisashi、Kera Takeshi、Hirayama Ryo、Hirano Hirohiko、Fujiwara Yoshinori、Ihara Kazushige、Kojima Motonaga、Obuchi Shuichi
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: 30 Issue: 4 Pages: 283-291

    • DOI

      10.1007/s40520-017-0781-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Kinematic Analysis of Step Initiation by Stroke Patients2017

    • Author(s)
      大沼 亮、星 文彦、西原 賢
    • Journal Title

      Rigakuryoho Kagaku

      Volume: 32 Issue: 6 Pages: 809-815

    • DOI

      10.1589/rika.32.809

    • NAID

      130006262662

    • ISSN
      1341-1667, 2434-2807
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 超音波画像を用いた大腿四頭筋の筋厚と輝度の分析による高齢者の運動機能と骨格筋との比較2016

    • Author(s)
      西原 賢、坂本 哲也
    • Journal Title

      日本超音波骨軟組織学術研究

      Volume: 15 Pages: 7-12

    • Related Report
      2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed
  • [Presentation] Relationship between ultrasonic echo intensities of the skeletal muscle and liver in elderly and young individuals2017

    • Author(s)
      Ken Nishihara, Hisashi Kawai, Kazuhiko Hara, Fumihiko Hoshi
    • Organizer
      The 21st IAGG World Congress of Gerontology & Geriatrics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 超音波エコーを用いた肘窩の採血・静脈注射部位の検討2016

    • Author(s)
      五味敏昭、木村明彦、成瀬秀夫、小山浩司、西原 賢、金村尚彦
    • Organizer
      第121回日本解剖学会総会・全国学術集会
    • Place of Presentation
      ビッグパレットふくしま、郡山市
    • Year and Date
      2016-03-28
    • Related Report
      2015 Research-status Report
  • [Presentation] 高齢者の超音波画像に基づいた運動器の「質」の分析2015

    • Author(s)
      西原 賢、坂本 哲也
    • Organizer
      第15回日本超音波骨軟組織学会学術総会
    • Place of Presentation
      富士通関西システムラボラトリ、大阪市
    • Year and Date
      2015-10-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 超音波画像処理による「筋の質」と運動機能との比較2015

    • Author(s)
      西原 賢
    • Organizer
      運動器超音波研究会シンポジウム
    • Place of Presentation
      早稲田大学東伏見キャンパス、東京都
    • Year and Date
      2015-07-03
    • Related Report
      2015 Research-status Report
    • Invited

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Published: 2015-04-16   Modified: 2020-03-30  

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