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Visual neural basis related with human adaptive locomotion

Research Project

Project/Area Number 15K01506
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Developmental mechanisms and the body works
Research InstitutionTeikyo University

Principal Investigator

SAKIHARA KOTOE  帝京大学, 医療技術学部, 講師 (40423115)

Co-Investigator(Kenkyū-buntansha) 稲垣 真澄  国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 知的・発達障害研究部, 部長 (70203198)
奥住 秀之  東京学芸大学, 教育学部, 教授 (70280774)
中村 みほ  愛知県心身障害者コロニー発達障害研究所, 機能発達学部, 客員研究者 (70291945)
北 洋輔  国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 知的・発達障害研究部, 室長 (90627978)
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords適応的歩行 / 発達障害児
Outline of Final Research Achievements

We aimed to clarify the visual neural basis of children with Autistic Spectrum Disorder (ASD) about an adaptive locomotion. We recorded electroencephalogram (EEG) from typically developed children and children with ASD when they performed visual task of direction distinguish. All children showed N200 component in the right occiparietal cortex. The latency of N200 component was delated in the children with ASD compared with typically developed children. The children with ASD need more time for visuomotor process. Hierarchical multiple regression analysis was performed for children with ASD between N200 latency, motor function (MABC2) and ASD severity (SRS). ASD severity with motor dysfunction estimated the visual recognition.

Academic Significance and Societal Importance of the Research Achievements

ASD児は社会性の認知障害と歩行障害などの運動障害を並存するが,それらと脳機能との関連は明らかにされていなかった.本研究では,社会性障害に運動障害が併存した場合に彼らの視覚認知脳機能を予測できることが示された.

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (5 results)

All 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results) Presentation (3 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Applicability of the Movement Assessment Battery for Children-Second Edition to Japanese children: A study of the Age Band 22016

    • Author(s)
      Kita Y,Suzuki K,Hirata S,Sakihara K、Inagaki M,Nakai A
    • Journal Title

      Brain and Development

      Volume: 38 Issue: 8 Pages: 706

    • DOI

      10.1016/j.braindev.2016.02.012

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Uniqueness of action monitoring in children with autism spectrum disorder: Response types and temporal aspects2016

    • Author(s)
      Kota Suzuki, Yosuke Kita, Kotoe Sakihara, Shogo Hirata, Ryusuke Sakuma, Hideyuki Okuzumi, Masumi Inagaki
    • Journal Title

      Journal of Clinical and Experimental Neuropsychology

      Volume: 39 Issue: 8 Pages: 803

    • DOI

      10.1080/13803395.2016.1266308

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Cognitive function in 15 patients with adrenoleukodystrophy (ALD) after 5 to 20 years of hematopoietic stem cell transplantation (HSCT).2017

    • Author(s)
      Kaga M, Sakihara K, Gunji A, Nakamura M, Inagaki M, Kato S
    • Organizer
      12th European Paediatric Neurology Society Congress
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 脳波解析に基づく発達障害児の脳機能評価-ASDとAD/HDを中心に-2016

    • Author(s)
      崎原ことえ,軍司敦子,加賀佳美,中川栄二,稲垣真澄
    • Organizer
      第46回臨床神経生理学会
    • Place of Presentation
      郡山
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Forty nine-years follow-up of a patient with Landau-Kleffner syndrome.2016

    • Author(s)
      Kaga M,Nakamura M,Gunji A,Sakihara K,Inagaki M,Suzuki M
    • Organizer
      14th International Child Neurology Congress
    • Place of Presentation
      Amsterdam
    • Year and Date
      2016-05-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2020-03-30  

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