Effects of non-invasive electrical stimulation on excitability of neurons during walking

• Project/Area Number: 15K01508
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Developmental mechanisms and the body works
• Research Institution: Doshisha University
• Principal Investigator: Kamibayashi Kiyotaka 同志社大学, スポーツ健康科学部, 准教授 (70415363)
• Project Period (FY): 2015-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 歩行 / 電気刺激 / 筋電図 / 経頭蓋磁気刺激

Outline of Final Research Achievements

The purpose of this study was to clarify what effects on muscle activity and neural excitability would occur by applying electrical stimulation to muscles or sensory nerves during normal human walking. The external stimuli given during walking in healthy subjects caused changes in muscle activation levels, common drive to motoneurons, and excitability of the corticospinal tract to the target muscle.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果から、ヒトの二足歩行時に与えた非侵襲的な電気刺激によって適応が生じ、刺激をオフにした後にも筋活動などに変化が短期間みられたことから、刺激方法を工夫することで回復をより促しやすい歩行リハビリテーションへと発展することが期待される。また、体重免荷した歩行では免荷による効果が筋によって異なることから、リハビリテーションにおいて筋ごとに注意が必要となることが示された。

Research Products

• [Journal Article] Training machines for astronauts equipped at NASA Johnson Space Center (2017)
  • Author(s): 大平充宣，上林清孝，辻内伸好
  • Journal Title: 同志社スポーツ健康科学 Volume: 9 Issue: 9 Pages: 49-50
  • DOI: 10.14988/pa.2017.0000016346
  • NAID: 120006353927
  • ISSN: 18834132
  • URL: https://doshisha.repo.nii.ac.jp/records/25833
  • Year and Date: 2017-06-15
• [Presentation] Changes in the common synaptic drive to the ankle dorsiflexor muscle during split-belt walking in humans. (2019)
  • Author(s): Oshima A, Murai H., Tsujiuchi N, Kamibayashi K.
  • Organizer: 24th Annual Congress of European College of Sport Science
  • Int'l Joint Research
• [Presentation] Modulation of leg muscle activity during treadmill walking by varying body weight unloading. (2019)
  • Author(s): Kamibayashi K, Oshima A, Araki K, Tsujiuchi T, Ohira Y.
  • Organizer: 40th Annual Meeting of International Society for Gravitational Physiology
  • Int'l Joint Research
• [Presentation] Effect of body weight unloading on muscle activity and kinematics during walking. (2018)
  • Author(s): Kamibayashi K, Nishiyama S, Araki K, Tsujiuchi N, Ohira Y.
  • Organizer: 23nd Annual Congress of European College of Sport Science
  • Int'l Joint Research
• [Presentation] Analysis of gait characteristics with various levels of weight bearing using wearable motion measurement device. (2018)
  • Author(s): Araki K, Tsujiuchi N, Ito A, Ohira Y, Kamibayashi K.
  • Organizer: 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • Int'l Joint Research
• [Presentation] 装着型計測装置を用いた免荷歩行の特性解析と評価 (2018)
  • Author(s): 西山智士，辻内伸好，伊藤彰人，大平充宣，上林清孝，荒木啓輔
  • Organizer: 日本機械学会関西支部第93期定時総会講演会
• [Presentation] 月・火星環境では歩行における筋肉の活動はどう変わる？ (2017)
  • Author(s): 上林清孝
  • Organizer: 同志社大学宇宙医科学研究センターLaunch Symposium
  • Place of Presentation: 同志社大学（京都・京田辺市）
• [Presentation] Effect of body weight support on muscle activities during walking and running using a lower body positive pressure treadmill in healthy adults (2016)
  • Author(s): Kamibayashi K, Yoshida S, Wakahara T, Ishii K, Ohira Y
  • Organizer: XXI ISEK Congress
  • Place of Presentation: Chicago(USA)
  • Year and Date: 2016-07-05
  • Int'l Joint Research
• [Presentation] ヒトの身体運動における脳神経・筋活動の計測とリハビリテーションでの活用 (2016)
  • Author(s): 上林清孝
  • Organizer: 第30回同志社大学・けいはんな産学交流会
  • Place of Presentation: 同志社大学（京都・京田辺市）
• [Presentation] Development of a walking exercise prescription using an antigravity treadmill as a possible method for rehabilitation and /or training of astronauts before a flight for the Mars to the Moon (2015)
  • Author(s): Ohira Y, Kamibayashi K, Wakahara T, Tsujiuchi N, Ito A, Sekiguchi C
  • Organizer: 第53回同志社大学ハリス理化学研究所研究発表会
  • Place of Presentation: 恵道館（京都・京田辺市）
  • Year and Date: 2015-12-05