Development of prevention and treatment of sarcopenia by simple strength training under blood flow restriction
| Project/Area Number |
15K01553
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Seirei Christopher University |
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Principal Investigator |
YASUDA TOMOHIRO 聖隷クリストファー大学, 看護学部, 准教授 (20549604)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | サルコペニア / トレーニング / 血流制限 / 加圧トレーニング / 骨格筋 / CT / 調査 / 電気刺激 / 下肢 / 加圧 / 筋力トレーニング / 健康長寿 / 介護予防 / ロコモティブシンドローム |
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| Outline of Final Research Achievements |
Our results show that
1) Elastic band blood-flow restriction (BFR) training increases thigh muscle CSA as well as maximal muscle strength, but does not decrease vascular function in older women. 2) BFR training significantly decreased PmvO2, and enhanced mTOR signaling pathways in skeletal muscle using a rat model, which may play a role in diminishing muscle atrophy under various conditions in human studies. 3) Facilities under the guidance of appropriate BFR training leaders or instructors can achieve safe and beneficial effects, regardless of subject age, gender, or physical condition in 2016 just as back in 2006. 4)The long-term BFR training were a highly safe and effective training method for a patient (57 years) with knee meniscectomy.
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Report
(4 results)
Research Products
(47 results)
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[Journal Article] Muscle hypertrophy following blood flow-restricted low force isometric electrical stimulation in rat tibialis anterior: Role for muscle hypoxia.2018
Author(s)
Nakajima T, Koide S, Yasuda T, Hasegawa T, Yamasoba T, Obi S, Toyoda S, Nakamura F, Inoue T, Poole DC, Kano Y
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Journal Title
J Appl Physiol
Volume: 印刷中
Issue: 1
Pages: 134-145
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Effects of low-load, elastic band resistance training combined with blood flow restriction on muscle size and arterial stiffness in older adults.2015
Author(s)
Yasuda T, Fukumura K, Uchida Y, Koshi H, Iida H, Masamune K, Yamasoba T, Sato Y, Nakajima T.
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Journal Title
The Journals of Gerontology, Series A: Biological Sciences
Volume: 印刷中
Issue: 8
Pages: 950-958
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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