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Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure

Research Project

Project/Area Number 15K01702
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionTsukuba University of Technology

Principal Investigator

Miura Misa  筑波技術大学, 保健科学部, 准教授 (30612014)

Co-Investigator(Kenkyū-buntansha) 伊藤 修  東北大学, 医学系研究科, 大学院非常勤講師 (00361072)
平山 暁  筑波技術大学, 保健科学部, 教授 (20323298)
上月 正博  東北大学, 医学系研究科, 教授 (70234698)
Research Collaborator OOWADA Shigeru  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords高齢者 / 慢性腎不全 / 血液透析 / 透析中の運動 / 運動様式 / 運動耐容能 / 筋力 / 生化学変化 / 維持透析 / 透析中の運動療法 / 透析中の電気刺激 / 安全性 / 有効性 / 身体運動機能 / 生化学検査 / 外来透析 / 負荷量可変型エルゴメータ / 電動式エルゴメータ / RCT / 慢性腎不全患者 / 血液透析患者 / 腎臓リハビリテーション / 電動アシスト自転車 / 負荷量可変型自転車 / 透析効率
Outline of Final Research Achievements

We carried it out in multI centers and the total of 71 subjects divided it into control group(n=39), electric assist bicycle exercise (EA;n=10) groupthree groups of load quantity variableness type exercise (ER;n=22) groups. In the EA group, We carried out lower limbs exercise using the electric assist bicycle during dialysis for less than one hour at 4-hour dialysis time of twice a week of dialysis and continued it for 12 weeks. the change was not accepted in approximately intervention by the control group and fell to lower limbs muscular strength in the EA group, and skinfold thickness decreased in the ER group, and the increase of the brachial muscle cross section, exercise tolerance increase, balance improvement were recognized. No other parameters did not changed. However, EA and the ER were effective for elderly with end stage renal disease, there were different effects depends on exercise methods.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (31 results)

All 2017 2016 2015

All Journal Article (15 results) (of which Peer Reviewed: 10 results,  Open Access: 6 results,  Acknowledgement Compliant: 1 results) Presentation (12 results) (of which Int'l Joint Research: 8 results,  Invited: 1 results) Book (4 results)

  • [Journal Article] Training with an Electric Exercise Bike versus a Conventional Exercise Bike during Hemodialysis for Patients with End-stage Renal Disease: A Randomized Clinical Trial2017

    • Author(s)
      Miura M, Yoshizawa R, Oowada S, Hirayama A, Ito O, Kohzuki M, Maeba T.
    • Journal Title

      Progress in Rehabilitation Medicine

      Volume: 2 Issue: 0 Pages: n/a

    • DOI

      10.2490/prm.20170008

    • NAID

      130007042064

    • ISSN
      2432-1354
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of aerobic exercise during hemodialysis session on elderly patients: Results of one-year clinical controlled trial2017

    • Author(s)
      Ryo Yoshizawa, Misa Miura, Shigeru Oowada, Osamu Ito, Masahiro Kohzuki, Teruhiko Maeba
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 1-4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 視覚障害学生に対する喀痰吸引モデル使用の経験2017

    • Author(s)
      三浦美佐,上月正博,松下昌之助,平山暁,石塚和重
    • Journal Title

      ロービジョン学会誌

      Volume: 1 Pages: 1-5

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Renal rehabilitation: Present and future perspectives2017

    • Author(s)
      Misa Miura
    • Journal Title

      Physical Medicine and Rehabilitation Research

      Volume: 2(5) Pages: 20-20

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 理学療法士による運動とその効果.CKD患者のサルコペニア・フレイル2016

    • Author(s)
      三浦美佐,平山暁
    • Journal Title

      腎と透析

      Volume: 80.5 Pages: 745-750

    • Related Report
      2016 Research-status Report
  • [Journal Article] 2015 国際学会報告2016

    • Author(s)
      三浦美佐,平山 暁,大和田滋,前波輝彦,小川佳子,伊藤 修,上月正博
    • Journal Title

      筑波技術大学テクノレポート

      Volume: 23(2) Pages: 50-53

    • Related Report
      2016 Research-status Report
  • [Journal Article] Effects of ergometer exercise in an upright position on autonomic nervous activity in patients with Parkinson’s disease2016

    • Author(s)
      M Miura, N Ohkoshi , M Kohzuki, Y Ogawa, H Kinoshita, S Matsushita,T Sakuma, Y Matsui, O Ito
    • Journal Title

      NTUT Education of Disabilities

      Volume: 14 Pages: 23-25

    • NAID

      120005738225

    • Related Report
      2016 Research-status Report
  • [Journal Article] Physical exercise with multicomponent cognitive intervention for older adults with Alzheimer's disease: a 6-month randomized controlled trial2016

    • Author(s)
      Kim MJ, Han CW, Min KY, Cho CY, Lee CW, Ogawa Y, Mori E, Kohzuki M
    • Journal Title

      Dement Geriatr Cogn Dis Extra

      Volume: 6 Issue: 2 Pages: 222-232

    • DOI

      10.1159/000446508

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 慢性腎臓病患者における運動療法2016

    • Author(s)
      上月正博
    • Journal Title

      腎と骨代謝

      Volume: 29 Pages: 309-315

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 腎臓機能障害のリハビリテーション2016

    • Author(s)
      伊藤 修
    • Journal Title

      The Japanease Journal of Rehabilitation Medicine

      Volume: 53 Issue: 11 Pages: 834-838

    • DOI

      10.2490/jjrmc.53.834

    • NAID

      130005250464

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Attenuated a Decrease in Parasympathetic Nervous System Activity after Exercise.2016

    • Author(s)
      Jia T, Ogawa Y, Miura M, Ito O, Kohzuki M.
    • Journal Title

      PLoS One.

      Volume: 3 Issue: 2 Pages: 11-16

    • DOI

      10.1371/journal.pone.0148648

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Journal Title

      F1000 Research

      Volume: 1 Pages: 421-421

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] パーキンソン病患者に対する自転車運動での身体機能改善効果の臨床試験.2015

    • Author(s)
      三浦美佐.
    • Journal Title

      筑波技術大学テクノレポート

      Volume: 23(1) Pages: 193-193

    • NAID

      120005678881

    • Related Report
      2015 Research-status Report
  • [Journal Article] 高齢血液透析患者に関する廃用予防についての研究.2015

    • Author(s)
      三浦美佐.
    • Journal Title

      筑波技術大学テクノレポート

      Volume: 23(1) Pages: 191-192

    • NAID

      120006510947

    • Related Report
      2015 Research-status Report
  • [Journal Article] Expression of (pro)renin receptor and its upregulation by high salt intake in the rat nephron.2015

    • Author(s)
      Rong R, Ito O, Mori N, Muroya Y, Tamura Y, Mori T, Ito S, Takahashi K, Totsune K, Kohzuki M.
    • Journal Title

      Peptides.

      Volume: 63 Pages: 156-62

    • DOI

      10.1016/j.peptides.2014.12.007

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] サルコペニア・フレイルへの腎臓リハビリテーション的アプローチ2017

    • Author(s)
      三浦美佐
    • Organizer
      日本腎臓リハビリテーション学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 性腎臓病進行抑制のため自宅での電気刺激療法を試みた1症例2017

    • Author(s)
      三浦美佐,斎藤知栄,平山暁,伊藤修,上月正博,山縣邦弘
    • Organizer
      日本腎臓リハビリテーション学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Comparison of electric bike exercise to conventional bicycle training during hemodialysis sessions on physical function in patients with end stage renal disease2016

    • Author(s)
      M Miura , R Yoshizawa, S Oowada, A Hirayama, O Ito, Y Hirayama, M Kohzuki, T Maeba
    • Organizer
      American Society of Nephrology(Kidney Week 2016)
    • Place of Presentation
      Chicago, America
    • Year and Date
      2016-11-15
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 血液透析中の運動療法または下肢電気刺激は身体機能を改善する:多施設共同治験2016

    • Author(s)
      [3]平山真喜子,吉澤亮,戀塚ゆかり,鈴木志穂,鈴木綾子, 三浦美佐,大和田滋,前波輝彦
    • Organizer
      第 6 回日本腎臓リハビリテーション学会
    • Place of Presentation
      大阪国際会議場, 大阪府
    • Year and Date
      2016-06-09
    • Related Report
      2016 Research-status Report
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end-stage renal disease: study protocol for a multicenter controlled trial2016

    • Author(s)
      M. Miura, M. Kohzuki, S. Oowada, Y. Hirayama, O. Ito,A. Hirayama.
    • Organizer
      10th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2016-05-29
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 透析中の運動療法での高齢透析患者の酸化ストレス消去活性への影響2016

    • Author(s)
      三浦美佐,平山暁, 大和田滋,平山陽,伊藤修,上月正博
    • Organizer
      第 28 回腎とフリーラジカル研究会
    • Place of Presentation
      つくば国際会議場, 茨城県
    • Related Report
      2016 Research-status Report
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients: Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Hirayama Y, Ito O, Kohzuki M.
    • Organizer
      2015 ASN
    • Place of Presentation
      San Diego, America
    • Year and Date
      2015-11-03
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Chronic kidney disease : a new target of cardiac rehabilitation.2015

    • Author(s)
      Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of comprehensive rehabilitation in non-alcoholic fatty liver disease (NAFLD) with obesity.2015

    • Author(s)
      Ito O, Suzuki F, Takahashi T, Sakata Y, Mori N, Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of Aerobic Training and Electrical Stimulation to Skeletal Muscles during Hemodialysis for Patients with End-Stage Renal Disease.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of Ergometer Exercise in an Upright or Supine Position on Autonomic Nervous Activity in Patients with Parkinson’s disease.2015

    • Author(s)
      Miura M, Ookoshi N, Ito O, Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      52th ERA-EDTA
    • Place of Presentation
      London, England
    • Year and Date
      2015-05-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Book] 新編内部障害のリハビリテーション 第2版2017

    • Author(s)
      上月正博
    • Total Pages
      497
    • Publisher
      医歯薬出版
    • ISBN
      9784263215784
    • Related Report
      2017 Annual Research Report
  • [Book] よくわかる内部障害の運動療法2016

    • Author(s)
      上月正博
    • Total Pages
      282
    • Publisher
      医歯薬出版
    • Related Report
      2016 Research-status Report
  • [Book] そうだったんだ!リハビリテーション2016

    • Author(s)
      上月正博
    • Total Pages
      238
    • Publisher
      文光堂
    • Related Report
      2016 Research-status Report
  • [Book] 重複障害のリハビリテーション2015

    • Author(s)
      上月正博
    • Total Pages
      581
    • Publisher
      三輪書店
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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