| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Researches on adiponectin have been focused on the relationship between adiponectin in blood and diseases. These researches show that adiponectin in blood and diseases have inverse correlation because adiponectin is anti-metabolic syndrome hormone. Recently, we discovered organ-bound adiponectin as a novel adiponectin. We assessed the relationship between heart-bound adiponectin and hypertension or cardiac hypertrophy. The result showed that heart-bound adiponectin, but not serum adiponectin, inversely correlated with cardiac hypertrophy. Further analysis of gene expression in heart showed that there are genes might be involved in hypertension and cardiac hypertrophy via heart-bound adiponectin.
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