Combined effects of jump exercise and Korean Red Ginseng on trabecular architecture and strength in rats

Research Project

Project/Area Number	15K01738
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Applied health science
Research Institution	Kawasaki University of Medical Welfare
Principal Investigator	Ju YongIn 川崎医療福祉大学, 医療技術学部, 講師 (00389016)
Project Period (FY)	2015-04-01 – 2019-03-31
Project Status	Completed (Fiscal Year 2018)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	ジャンプ運動 / 紅参 / 骨微細構造 / 骨強度 / マイクロCT / 有限要素法 / ３次元骨梁構造 / 三次元骨梁構造
Outline of Final Research Achievements	Recently, one shows an interesting result in that Korean Red Ginseng prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis. However, effects of Korean Red Ginseng on the trabecular bone architecture and strength and its mechanism has not been fully clarified yet. In this project, we have evaluated the combined effects of jump exercise coupled with Korean Red Ginseng in young and ovariectomized rats.
Academic Significance and Societal Importance of the Research Achievements	我が国において高齢者人口の増加に伴う骨粗鬆症の患者数の増加が予想されているが、まだ、この疾患の有効な予防・治療方法が確立されていないのが現状である。本研究によって得られた結果は、骨粗鬆症予防のための安全な健康機能食品の開発のみならず、代替医学的接近にも繋がるものであり、本研究成果による国民の骨健康・医療への貢献が期待される。