The relevance of infant-care behavior and a hormone level in the male of common marmoset.

• Project/Area Number: 15K01791
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Childhood science (childhood environment science)
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: Ikeda Akiko 国立研究開発法人国立精神・神経医療研究センター, 微細構造研究部, 研究生 (30511232)
• Co-Investigator(Renkei-kenkyūsha): Ichinohe Noritaka 国立研究開発法人国立精神・神経医療研究センター, 神経研究所, 部長 (00250598) ; Kawai Nobuyuki 名古屋大学, 大学院情報科学研究科, 准教授 (30335062)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: マーモセット / 父親 / 養育 / ホルモン / 育児

Outline of Final Research Achievements

The nurture of father is important to the growth and development of offspring. Common marmosets are a primate closely related with human-beings, and the father take care of offspring.In this study, we confirmed that salivary cortisol level of marmoset reflects blood cortisol level, and it was found that stress condition can be measured only by saliva sample collection.We succeeded in marmoset spontaneously chewing swab. We developed a way to use this method to collect saliva of marmosets in the home cage at any time.

Research Products

• [Journal Article] Inequity aversion is observed in common marmosets but not in marmoset models of autism induced by prenatal exposure to valproic acid. (2018)
  • Author(s): Yasue M, Nakagami A, Nakagaki K, Ichinohe N, Kawai N
  • Journal Title: Behav Brain Res. Volume: 234 Pages: 36-40
  • DOI: 10.1016/j.bbr.2018.01.013
  • Peer Reviewed / Open Access
• [Journal Article] Indifference of marmosets with prenatal valproate exposure to third-party non-reciprocal interactions with otherwise avoided non-reciprocal individuals. (2015)
  • Author(s): Yasue, M., Nakagami, A., Banno, T., Nakagaki, K., Ichinohe, N., Kawai, N.
  • Journal Title: Behavioural Brain Research Volume: 292 Pages: 323-326
  • DOI: 10.1016/j.bbr.2015.06.006
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] マーモセットにおける胎生期バルプロ酸暴露と不公平忌避 (2017)
  • Author(s): 安江みゆき、中神明子、中垣慶子、一戸紀孝、川合伸幸
  • Organizer: 日本心理学会 第81回大会
• [Presentation] マーモセットのコルチゾール分泌機能にバルプロ酸が与える影響 (2017)
  • Author(s): 中神明子、安江みゆき、中垣慶子、一戸紀孝、川合伸幸
  • Organizer: 日本心理学会 第81回大会
• [Presentation] 霊長類の自閉症モデルの行動評価 (2016)
  • Author(s): 川合伸幸, 中神明子, 安江みゆき, 坂野拓, 中垣慶子, 一戸紀孝
  • Organizer: 第6回日本マーモセット研究会大会
  • Place of Presentation: 東京
  • Year and Date: 2016-12-12
• [Presentation] Do primate models of autism care other individuals when they receive less valuable reward than other individuals? (2016)
  • Author(s): M. YASUE, A. NAKAGAMI, K. NAKAGAKI, N. ICHINOHE, N. KAWAI
  • Organizer: 日本動物心理学会第76回大会
  • Place of Presentation: 札幌
  • Year and Date: 2016-11-23
• [Presentation] A new non-invasive method to measure cortisol levels from marmoset saliva． (2016)
  • Author(s): A. NAKAGAMI, M. YASUE, K. NAKAGAKI, N. ICHINOHE, N. KAWAI
  • Organizer: 日本動物心理学会第76回大会
  • Place of Presentation: 札幌
  • Year and Date: 2016-11-23
• [Presentation] Marmosets with fetal exposure to valproic acid fail to recognize third-party non-reciprocal interactions． (2016)
  • Author(s): Nobuyuki Kawai, Miyuki Yasue, Akiko Nakagami, Taku Banno, Noritaka Ichinohe
  • Organizer: The 31st International Congress of Psychology (ICP)
  • Place of Presentation: 横浜
  • Year and Date: 2016-07-24
  • Int'l Joint Research
• [Presentation] A primate model for autism with common marmosets show behavioral deficits in the threemajor symptoms of autism． (2016)
  • Author(s): Akiko Nkagami, Miyuki Yasue, Taku Banno, Keiko Nakagaki, Noritaka Ichinohe, Nobuyuki Kawai
  • Organizer: The 31st International Congress of Psychology (ICP)
  • Place of Presentation: 横浜
  • Year and Date: 2016-07-24
  • Int'l Joint Research
• [Presentation] Plasma oxytocin level of male marmoset in pre- and postnatal period. (2015)
  • Author(s): Akiko Nakagami, Miyuki Yasue, Keiko Nakagaki, Noritaka Ichinohe, Nobuyuki Kawai
  • Organizer: 日本動物心理学会第75回大会
  • Place of Presentation: 日本女子大学（東京）
  • Year and Date: 2015-09-10
• [Presentation] Marmoset models of autism did not avoid non-reciprocal human individuals (2015)
  • Author(s): Miyuki Yasue, Akiko Nakagami, Taku Banno, Keiko Nakagaki, Noritaka Ichinohe, Nobuyuki Kawai
  • Organizer: 日本動物心理学会第75回大会
  • Place of Presentation: 日本女子大学（東京）
  • Year and Date: 2015-09-10
• [Presentation] Primate models of autism failed to discriminate third-party reciprocal/non-reciprocal exchange between human actors (2015)
  • Author(s): Miyuki Yasue, Akiko Nakagami, Taku Banno, Keiko Nakagaki, Noritaka Ichinohe, Nobuyuki Kawai
  • Organizer: Tokyo Lectures in Language Evolution
  • Place of Presentation: The University of Tokyo (Tokyo)
  • Year and Date: 2015-04-02