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Decoding others' reward signals affecting valuation of self rewards - a role of the primate lateral hypothalamus

Research Project

Project/Area Number 15K04200
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Experimental psychology
Research InstitutionNational Institute for Physiological Sciences (2017)
Kansai Medical University (2015-2016)

Principal Investigator

NORITAKE Atsushi  生理学研究所, システム脳科学研究領域, 助教 (80407684)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords報酬 / 社会 / 視床下部外側野 / 自己および他者 / 霊長類 / 学習 / 自己と他者
Outline of Final Research Achievements

Primates, including human beings, are thought to be social animals in nature. Cortical neuron mechanisms of social learning and social adaptation have often been discussed, whereas subcortical neuron mechanisms remain unclear. This study investigated whether and how information of reward to others influenced anticipatory behavior for rewards to oneself and the neuronal representation in the primate lateral hypothalamus. Our physiological and pharmacological experiments have revealed that neurons in the lateral hypothalamus encoded signals of self-reward and other-reward values in an integrated manner (subjective value) and that their activity was profoundly involved in the anticipatory licking behavior for rewards. These findings may extend current learning theories based on self-reward information to those based on not only self-reward but also other-reward information and provide valuable insights into our social behavior.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2018 2017 2016 2015 Other

All Presentation (6 results) (of which Int'l Joint Research: 3 results) Remarks (1 results)

  • [Presentation] サル大脳皮質・皮質下回路における自己および他者の報酬情報表現2018

    • Author(s)
      則武厚
    • Organizer
      第7回新潟脳研-霊長研-生理研合同シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Neural networks for social reward valuation in the macaque brain2017

    • Author(s)
      Noritake A
    • Organizer
      The 7th NIPS/CIN Joint Symposium
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multiple social reward signals in the macaque brain2017

    • Author(s)
      Noritake A
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 霊長類ドパミン細胞の活動は他者への報酬見込みによって影響を受ける Activity of primate dopamine neurons is influenced by the prospect of others’ reward2016

    • Author(s)
      Noritake A., Isoda M.
    • Organizer
      第39回日本神経科学大会(パシフィコ横浜)
    • Place of Presentation
      Pacifico Yokohama (Yokohama, Japan)
    • Related Report
      2016 Research-status Report
  • [Presentation] Social reward signals in primate lateral hypothalamic neurons: comparison with prefrontal and midbrain dopamine neurons2016

    • Author(s)
      Noritake A., Isoda M.
    • Organizer
      第47回北米神経科学大会(サンディエゴコンベンションセンター)
    • Place of Presentation
      San Dieago Convention Center (San Diego, USA)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Social reward valuation in primate midbrain dopamine cells2015

    • Author(s)
      Noritake A., Isoda M.
    • Organizer
      第45回北米神経科学大会
    • Place of Presentation
      シカゴ(アメリカ合衆国)
    • Year and Date
      2015-10-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 生理学研究所 システム脳科学研究領域 認知行動発達機構研究部門

    • URL

      https://www.nips.ac.jp/dbd/dbd_ja/index.html

    • Related Report
      2017 Annual Research Report

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Published: 2015-04-16   Modified: 2019-03-29  

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