Development of component technology for scanning microinjection microscope
| Project/Area Number |
15K04678
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Thin film/Surface and interfacial physical properties
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| Research Institution | Kogakuin University |
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Principal Investigator |
Takami Tomohide 工学院大学, 教育推進機構(公私立大学の部局等), 教授 (40272455)
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| Co-Investigator(Renkei-kenkyūsha) |
IWATA Futoshi 静岡大学, 学術院工学領域, 教授 (30262794)
TAKAKUWA Yuji 東北大学, 多元物質科学研究所, 教授 (20154768)
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| Research Collaborator |
SUGAWARA Takeshi 広島大学, 大学院理学研究科, 特任助教 (60713005)
TATE Shin-ichi 広島大学, 大学院理学研究科, 教授 (20216998)
SAITO Mikako 東京農工大学, 大学院工学研究院, 准教授 (20291346)
MATSUOKA Hideaki 東京農工大学, 大学院工学研究院, 名誉教授 (10143653)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ナノピペット / 走査型プローブ顕微鏡 / 細胞工学 / イオン選別 / 走査プローブ顕微鏡 / 触媒 / ナノ粒子 / 回転振動機構 / 真空コンダクタンス / 交流電解研磨 / アクチュエータ / コーティング |
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| Outline of Final Research Achievements |
We have developed the following three element technologies to realize scanning microinjection microscope. (1) Motion control during the penetration of the pipette into the cell membrane during injection (2) Development of a non-destructive evaluating method of the cleanliness of the nanopipette inner wall by measuring the entrance pressure dependence of the vacuum conductance through a nanopipette set between two vacuum chambers in order to increase the accuracy of substance injection into cells during injection, and (3) Development of ion-selective nanopipette probe containing ion-selective membrane and establishment of the electrochemical etching of platinum electrode used in scanning pipette microscope.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Argon gas flow through glass nanopipette2016
Author(s)
Tomohide Takami, Kiwamu Nishimoto, Tadahiko Goto, Shuichi Ogawa, Futoshi Iwata, and Yuji Takakuwa
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Journal Title
Japanese Journal of Applied Physics
Volume: 55
Issue: 12
Pages: 125202-125202
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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