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Preparation of single crystal region of lipid cubic phase and its application to phase transition studies

Research Project

Project/Area Number 15K05243
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biological physics/Chemical physics/Soft matter physics
Research InstitutionShizuoka University

Principal Investigator

Oka Toshihiko  静岡大学, 電子工学研究所, 准教授 (60344389)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsリオトロピック液晶 / キュービック相 / 相転移 / 単結晶作成 / X線結晶構造解析 / 2型キュービック相 / 単結晶 / II型キュービック相 / II型ヘキサゴナル相 / 単結晶領域作成 / 脂質 / X線回折
Outline of Final Research Achievements

Lyotropic liquid crystal is composed of two components such as lipid and water. Phase transition and structural analysis of lyotropic liquid crystal cubic phase were carried out. For the phase transition from cubic phase to another cubic phase, the orientational relationship before and after the phase transition was clarified. Based on this, a model of phase transition was constructed. Moreover, I did X-ray single crystal structural study of the cubic phase for the first time in the world and showed that the fluctuation of the bilayer membrane depends on the place from the obtained electron density map. I also studied how to create a single domain of lyotropic liquid crystal hexagonal phase.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (11 results)

All 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] Small-Angle X-ray Crystallography on Single-Crystal Regions of Inverse Bicontinuous Cubic Phases: Lipid Bilayer Structures and Gaussian Curvature-Dependent Fluctuations2017

    • Author(s)
      Toshihiko Oka
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 121 Issue: 50 Pages: 11399-11409

    • DOI

      10.1021/acs.jpcb.7b08589

    • NAID

      120006540612

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two distinct cylinder arrangements in monodomains of a lyotropic liquid crystalline hexagonal II phase: monodomains with straight cylinders and ringed cylinders in capillaries2016

    • Author(s)
      Toshihiko Oka* and Noboru Ohta
    • Journal Title

      Langmuir

      Volume: 32 Issue: 30 Pages: 7613-7620

    • DOI

      10.1021/acs.langmuir.6b00996

    • NAID

      120006324047

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Transformation between inverse bicontinuous cubic phases of a lipid from diamond to gyroid2015

    • Author(s)
      Toshihiko Oka
    • Journal Title

      Langmuir

      Volume: 31 Issue: 41 Pages: 11353-11359

    • DOI

      10.1021/acs.langmuir.5b02180

    • NAID

      120005844846

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 脂質キュービック相の小角X線結晶構造解析2017

    • Author(s)
      岡 俊彦
    • Organizer
      第 68 回コロイドおよび界面化学討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 脂質キュービック相の構造解析2017

    • Author(s)
      岡俊彦
    • Organizer
      日本物理学会 第72回年次大会
    • Place of Presentation
      大阪大学豊中キャンパス(大阪府豊中市)
    • Related Report
      2016 Research-status Report
  • [Presentation] Single Crystallization of an Inverse Bicontinuous Cubic Phase of a Lipid and Applications to Phase Transition Studies2016

    • Author(s)
      Toshihiko Oka
    • Organizer
      Boden Research Conference 2016, Animal Vegetal Mineral?
    • Place of Presentation
      Yallingup, Western Australia
    • Year and Date
      2016-09-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 脂質モノオレインのキュービック相間転移における方位関係:ダイアモンドージャイロイド転移2016

    • Author(s)
      岡 俊彦
    • Organizer
      日本物理学会 第71回年次大会(2016年)
    • Place of Presentation
      東北学院大学 仙台市
    • Year and Date
      2016-03-20
    • Related Report
      2015 Research-status Report
  • [Presentation] Orientational Relationships In Transformations Between Three Inverse Bicontinuous Cubic Phases of a Lipid2016

    • Author(s)
      岡俊彦
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Related Report
      2016 Research-status Report
  • [Presentation] リオトロピック液晶Ⅱ型キュービック相の単結晶領域作成2015

    • Author(s)
      岡 俊彦
    • Organizer
      第5回ソフトマター研究会
    • Place of Presentation
      東北大学 仙台市
    • Year and Date
      2015-12-17
    • Related Report
      2015 Research-status Report
  • [Presentation] リオトロピック液晶Ⅱ型キュービック相の単結晶領域作成とその相転移研究への応用2015

    • Author(s)
      岡 俊彦
    • Organizer
      日本学術振興会 情報科学用有機材料第142委員会 合同研究会
    • Place of Presentation
      PORTA(ポルタ)神楽坂7F会議室 (東京理科大学)(東京都新宿区)
    • Year and Date
      2015-11-20
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Transformation between inverse bicontinuous cubic phases of a lyotropic liquid crystal2015

    • Author(s)
      Toshihiko Oka
    • Organizer
      The 17 Takayanagi Kenjiro Memorial Symposium
    • Place of Presentation
      静岡大学浜松キャンパス(静岡県浜松市)
    • Year and Date
      2015-11-17
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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