| Project/Area Number |
15K05250
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Biological physics/Chemical physics/Soft matter physics
|
|---|
| Research Institution | Tokyo Metropolitan University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
岡本 隆一 岡山大学, 異分野基礎科学研究所, 特任講師 (10636385)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | マイクロレオロジー / ソフトマター / 細胞 / 異常拡散 / 揺動散逸定理 / マイクロマシン / マイクロスイマー / ブラウン・ラチェット |
|---|
| Outline of Final Research Achievements |
With the development of the new experimental technique called microrheology, many knowledges concerning cell rheology have been accumulating all over the world in the last decade. In this research project, with the aim to understand the universal behaviors in cell rheology within soft matter physics and nonequilibrium physics, we have developed fundamental theories for microrheology that is applicable to inhomogeneous and nonequilibrium systems. Furthermore, we have established a new microrheology method that is suitable for investigating mechanical responses in cells coated with biomembranes. In particular, we have established the followings: (i) basic theory for membrane microrhelogy, (ii) active microrheology in multi-component media, and (iii) detection of non-thermal fluctuations by using microrhelogy methods.
|
