Development of stimuli-responsive dynamic cooperative catalyst toward spatiotemporal control of chemical reaction and application to multi-state reaction control
| Project/Area Number |
15K05437
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
Imahori Tatsushi 東京理科大学, 工学部工業化学科, 准教授 (90433515)
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| Co-Investigator(Renkei-kenkyūsha) |
UCHIYAMA MASANOBU 東京大学, 大学院薬学系研究科, 教授 (00271916)
KURIHARA SEIJI 熊本大学, 大学院自然科学研究科(工), 教授 (50225265)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 刺激応答性触媒 / 化学反応制御 / 光応答性 / アゾベンゼン / スチルベン / 位置選択性切り替え / 熊田カップリング反応 / 協同機能性触媒 / 光応答性触媒 |
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| Outline of Final Research Achievements |
In this study, we tried to develop various kinds of stimuli-responsive dynamic catalysts by using various stimuli to demonstrate spatiotemporal control of chemical reaction and to accomplish multi-stage control of chemical reaction. We have developed some stimuli-responsive dynamic catalysts, such as stimuli-responsive acid-base-combined catalyst and stimuli-responsive Lewis acid catalyst, that switch the catalytic activities based on photo- and thermal-responsive isomerization of azobenzene. However, development of stimuli-responsive dynamic catalysts that utilize photo-isomerization of stilbene has not been accomplished. Furthermore, stimuli-responsive dynamic catalysts that switch the catalytic functions other than catalytic activity have not been developed. Therefore, multi-stage control of chemical reaction utilizing the stimuli-responsive dynamic catalysts still has not been demonstrated.
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Report
(4 results)
Research Products
(59 results)
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[Journal Article] Synthesis and stereochemical properties of chiral hetero[7]helicenes structured by a benzodiheterole ring core2017
Author(s)
Sachie Arae, Takaaki Mori, Takahiro Kawatsu, Daiki Ueda, Yusuke Shigeta, Nobutsugu Hamamoto, Hitoshi Fujimoto, Michinori Sumimoto, Tatsushi Imahori, Kazunobu Igawa, Katsuhiko Tomooka, Tharmalingam Punniyamurthy, Ryo Irie
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Journal Title
Chemistry Letters
Volume: 46
Issue: 8
Pages: 1214-1216
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease2016
Author(s)
Atsushi Kato, Izumi Nakagome, Kasumi Sato, Arisa Yamamoto, Isao Adachi, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yasuka Wasuka, Tatsushi Imahori, Yuichi Yoshimura, Hiroki Takahata and Shuichi Hirono
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Journal Title
Org. Bio. Chem.
Volume: 14
Issue: 3
Pages: 1039-1048
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Synthesis, Stereochemical Characteristics, and Coordination behavior of 2,2’-Binaphthyl-1,1’-bisisoquinoline as a New Axially Chiral Bidentate Ligand2015
Author(s)
Takahiro Kawatsu, Hiroki Tokushima, Yuya Takedomi, Tatsushi Imahori, Kazunobu Igawa, Katsuhiko Tomooka, Ryo Irie
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Journal Title
ARKIVOC
Volume: iv
Issue: 4
Pages: 161-175
DOI
Related Report
Peer Reviewed
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