| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
To achieve high efficiency and low environmental load required for modern asymmetric catalysts, we developed an asymmetric catalyst directed to "dynamic reaction field control", in which different asymmetric reaction fields are controlled depending on catalyst preparation conditions, achieving chemoselective and stereoselective asymmetric reactions. DFT calculations clarified major factors of high selectivities based on combined-acid function and hydrogen bonding network. Specifically, chiral bisamidine ligands were developed as a key framework incorporating different catalytic functions. Selectively preparaed combined-acid catalysts or multinuclear-metal catalysts were employed to various asymmetric reactions.
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