| Project/Area Number |
15K05840
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Thermal engineering
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Research Collaborator |
SAKAI Rina 北里大学, 医療衛生学部, 准教授 (10383647)
YOSHIDA Kazuhiro 北里大学, 医療衛生学部, 助教 (10791379)
KIYOKAWA Sayaka
KAMO Shota
HATA Natsumi
MATSUSHITA Shiori
INOUE Minori
MATSUSHITA Nao
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 水構造化 / キセノンガス / 加圧溶解 / 板状材料表面 / 薄膜液 / 冷温保存 / 細胞障害低減効果 / ガラス表面 |
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| Outline of Final Research Achievements |
The purpose of this subject was to clarify the effect of damage reduction in cold storage (temperature range from -2 to 6℃) of cells by two approaches using pressurized dissolution of xenon gas and thin film solution inserted between the two surfaces of plate material on a cell level by structurization of water, paying attention to the inhibition effect of the substance transportation. As a result, firstly, it was clear that reduction of cell damage could be achieved by pressurized dissolution of xenon gas, and the optimal pressure (0.5 MPa) and temperature (4℃) were found; secondly, it was also clear that reduction of cell damage was achieved by using the thin film solution (approximately 20 micrometers in thickness) between two glass plates at cold storage of the cell.
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