Evaluation of effect of crystallographic factor on biodegradable behavior of Mg-Ca alloy

• Project/Area Number: 15K06486
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Structural/Functional materials
• Research Institution: Kobe University
• Principal Investigator: IKEO Naoko 神戸大学, 工学研究科, 助教 (80647644)
• Co-Investigator(Kenkyū-buntansha): 向井 敏司 神戸大学, 工学研究科, 教授 (40254429)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 生体内分解性材料 / マグネシウム / 生体内分解性マグネシウム / 集合組織 / 生体内分解性

Outline of Final Research Achievements

To develop biodegradable magnesium devices, it is important to comprehend the effect of microstructural properties. Therefore this study focused on evaluation of effect by crystallographic factor on biodegradable properties of magnesium alloys. From first principal calculation and electrochemical measurement, crystallographic anisotropy and alloying element was evaluated. In addition, the effect of grain size and texture on biodegradable properties were clarified by electrochemical tests.

Research Products

• [Journal Article] Fabrication of a magnesium alloy with excellent ductility for biodegradable clips (2016)
  • Author(s): Naoko IKEO ; Ryota NAKAMURA ; Kousuke NAKA ; Toshiaki HASHIMOTO ; Toshihiko YOSHIDA ; Takeshi URADE ; Kenji FUKUSHIMA ; Hikaru YABUUCHI ; Takumi FUKUMOTO ; Yonson Ku ; Toshiji MUKAI
  • Journal Title: Acta materialia Volume: 29 Pages: 468-476
  • DOI: 10.1016/j.actbio.2015.10.023
  • Peer Reviewed
• [Presentation] Effect of Additive Zinc on Mechanical Properties and Degradation Behavior of Magnesium (2018)
  • Author(s): Naoko IKEO, Kengo FUJIWARA, Yoo-jin KIM, Toshiji MUKAI
  • Organizer: TMS 2018
  • Int'l Joint Research
• [Presentation] 純マグネシウムの生体内分解性に及ぼす結晶粒径の影響 (2017)
  • Author(s): 加藤あおい，藤原健吾，池尾直子，向井敏司
  • Organizer: 平成28年度関西学生会学生員卒業研究発表講演会
  • Place of Presentation: 大阪大学吹田キャンパス
  • Year and Date: 2017-03-10
• [Presentation] マグネシウム - 亜鉛合金の分解性に及ぼす集合組織の影響 (2017)
  • Author(s): 加藤あおい、藤原健吾、池尾直子、向井敏司
  • Organizer: 日本金属学会 2017 年秋期講演大会(第 161 回)
• [Presentation] マグネシウムの生体内分解性に及ぼすカルシウム添加の影響 (2017)
  • Author(s): 干場太一、山口正剛、池尾直子、向井敏司
  • Organizer: 軽金属学会関西支部 H２９年度若手研究者・院生による研究発表会
• [Presentation] 生体内分解性 Mg-Ca 合金の異方性改善に対する第三元素の 添加効果 (2017)
  • Author(s): 宮居 秀地、山口 正剛、 池尾 直子、 向井 敏司
  • Organizer: 日本金属学会 2017 年秋期講演大会(第 161 回)
• [Presentation] 生体内分解性マグネシウム合金の機械的性質改善に対する添加元素の役割解明 (2017)
  • Author(s): 宮居 秀地
  • Organizer: 軽金属学会関西支部 H２９年度若手研究者・院生による研究発表会
• [Presentation] 強度および生体内分解速度の最適化に向けたMg-Zn合金のミクロ組織制御 (2016)
  • Author(s): 藤原健吾，KimYoojin，池尾直子，向井敏司
  • Organizer: 軽金属学会第131回秋期大会
  • Place of Presentation: 茨城大学水戸キャンパス
  • Year and Date: 2016-11-06
• [Presentation] 生体内分解性Mg-Zn合金の高強度化および分解性評価 (2016)
  • Author(s): 藤原健吾
  • Organizer: 日本金属学会
  • Place of Presentation: 東京理科大学葛飾キャンパス
  • Year and Date: 2016-03-22
• [Presentation] Strength ening and Degradation Behavior of Magnesium-Cal cium Binary Alloy Proceedings of Biomaterials International 2015 (2015)
  • Author(s): Naoko IKEO
  • Organizer: Biomaterials International 2015
  • Place of Presentation: Kenting, Taiwan
  • Year and Date: 2015-06-01
  • Int'l Joint Research