Improvement of Microwave-Dielectric Absorption Spectroscopic System for the Development of Dosimeter

• Project/Area Number: 15K06666
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Nuclear engineering
• Research Institution: University of Fukui
• Principal Investigator: IZUMI Yoshinobu 福井大学, 附属国際原子力工学研究所, 教授 (60252582)
• Research Collaborator: KOJIMA Takao 大阪府立大学, 助教 ; MATUO Youichirou 福井大学, 講師 ; SUNAGAWA Takeyoshi 福井工業大学, 教授
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
• Keywords: DNA / マイクロ波 / 誘電率 / 放射線 / 鎖切断

Outline of Final Research Achievements

Micro-wave dielectric absorption spectroscopy has been applied to dosimetry using DNAs. Enzyme-induced strand break of DNA could be estimated, and showing that yields of radiation-induced single- and double-strand breaks could be estimated. We succeeded in reduce the drift of measured value by simultaneous measurement of temperature and real-time calibration.

Research Products

• [Journal Article] Microwave Dielectric Absorption Spectroscopy Aiming at Novel Dosimetry Using DNAs (2017)
  • Author(s): Yoshinobu Izumi, Makoto Hirayama, Youichirou Matuo, Takeyoshi Sunagawa
  • Journal Title: Journal of Radiation Protection and Research Volume: 42 Issue: 1 Pages: 21-25
  • DOI: 10.14407/jrpr.2017.42.1.21
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Evaluation of DNA Damage Using Microwave Dielectric Absorption Spectroscopy (2016)
  • Author(s): Makoto Hirayama, Youichirou Matuo, Takeyoshi Sunagawa, Yoshinobu Izumi
  • Journal Title: Journal of Radiation Protection and Research Volume: 41 Pages: 339-343
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Evaluation of DNA Damage Using Microwave Dielectric Absorption Spectroscopy (2015)
  • Author(s): M. HIRAYAMA, Y. MATUO, T. SUNAGAWA and Y. IZUMI
  • Organizer: ISORD-8
  • Place of Presentation: Korea
  • Year and Date: 2015-07-14
  • Int'l Joint Research
• [Presentation] Microwave Dielectric Absorption Spectroscopy, Aiming at Novel Dosimetry Using DNAs (2015)
  • Author(s): Y. IZUMI, M. HIRAYAMA, Y. MATUO and T. SUNAGAWA
  • Organizer: ISORD-8
  • Place of Presentation: Korea
  • Year and Date: 2015-07-14
  • Int'l Joint Research