| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
In the central nervous system of the mammalian brain, three types of glial cells have been identified; astrocyte, microglia and oligodendrocyte. Among them, oligodendrocyte forms myelin around axons. Other types of glial cells might contribute to the synaptic functions of the brain by affecting the synapse formation/elimination.
In this research, I analyzed the precise structure of astrocyte and microglia by using CLEM (Correlative anaylysis of light- and electron- microscopy) method. Particularly, I succeeded the comprehensive three-dimensional reconstruct of the fine protrusions of single microglia.
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