Spatio-temporal genomic variation in wild plants: Integration of genome and field biology
| Project/Area Number |
15K06901
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Genome biology
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | シロイヌナズナ近縁種 / 集団ゲノム解析 / ニッチモデリング / 野生植物 / ゲノム / 適応遺伝子 / 集団構造 |
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| Outline of Final Research Achievements |
Adaptive genes were researched in Arabidopsis halleri subsp. gemmifera, close to a model plant Arabidopsis thaliana, collected from various environments in Japan. First, genome-wide association study taking account of population structure was used to clarify adaptive genes from whole genome sequencing data of collected multiple individuals. In addition, using the distribution data of alleles of the adaptive genes and environmental data in the collection point, modeling was performed on the geographic information system (GIS) to predict the distribution in the future environment. Furthermore, using plants that are far from model plants, I tried to apply the research approaches in A. halleri subsp. gemmifera.
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| Academic Significance and Societal Importance of the Research Achievements |
広域的な分布を持つ生物種は、時間的に変動する多様な環境に対して、局所的に適応することで分布範囲を拡大させてきたと考えられる。これまで、このような環境適応を担う遺伝子を直接解析することは、技術的に大きな困難を伴っていた。しかしながら本研究では、近年になって広く普及した次世代シーケンサーを用いて大量のDNA配列を解析することで、同一種内の複数個体の全ゲノム解読をおこなった。また、高性能でなおかつ安価な計算機を用いることで、大量のDNA配列データ解析と将来予測のための統計モデル解析から、適応遺伝子に基づく分布予測をおこなった。
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Report
(5 results)
Research Products
(19 results)
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[Journal Article] From the laboratory to the field: assaying histone methylation at FLOWERING LOCUS C in naturally growing Arabidopsis halleri.2016
Author(s)
Nishio, H., Buzas, D. M., Nagano, A. J., Suzuki, Y., Sugano, S., Ito, M., Morinaga, S.-I., Kudoh, H.
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Journal Title
Genes & Genetic Systems
Volume: 91
NAID
Related Report
Peer Reviewed
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[Journal Article] A genome scan for genes underlying microgeographic-scale local adaptation in a wild Arabidopsis species2015
Author(s)
Kubota, S., Iwasaki, T., Hanada, K., Nagano, A. J., Toyoda, A., Fujiyama, A., Sugano, S., Suzuki, Y., Hikosaka, K., Ito, M., and Morinaga, S.-I.
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Journal Title
PLOS Genetics
Volume: 11
Issue: 7
Pages: e1005361-e1005361
DOI
NAID
Related Report
Peer Reviewed / Open Access
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