| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
In the life sciences field, researchers have investigated nucleotide sequences and expression levels of transcripts (called transcriptome) working in a sample that constitutes an organism. They include the measurement of expression similarities between samples and the identification of genes differentially expressed between conditions of interest. In this research, we proposed to use Silhouette scores to objectively estimate the degree of separation between groups of interest. We confirmed that silhouettes is useful for exploring data with predefined group labels. It would help provide both an objective evaluation of the sample clustering results and insights into the differential expression results with regard to the compared groups.
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