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Molecular basis for flowering initiation by florigen

Research Project

Project/Area Number 15K06969
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Structural biochemistry
Research InstitutionKyoto University

Principal Investigator

Ohki Izuru  京都大学, 化学研究所, 特定研究員 (80418574)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords立体構造解析 / 植物ホルモン / 花成 / フロリゲン / 構造生物学 / 育種 / ホルモン受容体
Outline of Final Research Achievements

In higher plants, florigen is a mobile hormone that determines the flowering time, but its regulatory mechanism for floral induction remains unclear. In this study, we focused on anti-florigen, which suppresses floral induction antagonizing with florigen, to clarify the regulatory role in flowering. From the structural and biochemical analysis, anti-florigen was found to form a stable complex with florigen receptor on target receptor and inhibited a formation of florigen-receptor complex. The complex formation of florigen and anti-florigen against to the receptor is exchangeable, suggesting that the balance of the two complexes are important for floral induction.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (9 results)

All 2018 2017 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (7 results) (of which Invited: 1 results)

  • [Journal Article] Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization2018

    • Author(s)
      Fujita Hiroaki、Tokunaga Akira、Shimizu Satoshi、Whiting Amanda L.、Aguilar-Alonso Francisco、Takagi Kenji、Walinda Erik、Sasaki Yoshiteru、Shimokawa Taketo、Mizushima Tsunehiro、Ohki Izuru、Ariyoshi Mariko、Tochio Hidehito、Bernal Federico、Shirakawa Masahiro、Iwai Kazuhiro
    • Journal Title

      Cell Reports

      Volume: 23 Issue: 4 Pages: 1192-1204

    • DOI

      10.1016/j.celrep.2018.03.112

    • NAID

      120006460107

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] TFL1-Like Proteins in Rice Antagonize Rice FT-Like Protein in Inflorescence Development by Competition for Complex Formation with 14-3-3 and FD.2018

    • Author(s)
      Kaneko-Suzuki M, Kurihara-Ishikawa R, Okushita-Terakawa C, Kojima C, Nagano-Fujiwara M, Ohki I, Tsuji H, Shimamoto K, Taoka KI.
    • Journal Title

      Plant Cell Physiol.

      Volume: 59 Issue: 3 Pages: 458-468

    • DOI

      10.1093/pcp/pcy021

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 植物のメチル化DNA結合タンパク質の機能構造解析2017

    • Author(s)
      大木出、白川昌宏
    • Organizer
      第58回日本植物生理学会年会
    • Place of Presentation
      鹿児島大学郡元キャンパス(鹿児島県鹿児島市)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Research-status Report
  • [Presentation] 溶液NMRにおける超偏極技術の新たな展開と生体系への応用2017

    • Author(s)
      大木出
    • Organizer
      日本分光学会NMR分光部会講習会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 生体系の溶液NMRにおける超偏極技術の新たな展開2017

    • Author(s)
      大木出、藤咲貴大、池上貴久、白川昌宏
    • Organizer
      第56回NMR討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 植物のメチル化DNA結合タンパク質の構造解析2017

    • Author(s)
      大木出、尾野有菜、白川昌宏
    • Organizer
      生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 植物のメチル化DNA結合タンパク質の構造機能解析2016

    • Author(s)
      尾野有菜、大木出、竹下至、白川昌宏
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市西区)
    • Year and Date
      2016-12-01
    • Related Report
      2016 Research-status Report
  • [Presentation] 植物のメチル化DNA結合タンパク質の機能構造解析2016

    • Author(s)
      大木出、竹下至、白川昌宏
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市博多区)
    • Year and Date
      2016-06-09
    • Related Report
      2016 Research-status Report
  • [Presentation] 植物のメチル化DNA結合タンパク質の機能解析2015

    • Author(s)
      竹下至、大木出、白川昌宏
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市中央区)
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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