| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Moyamoya disease is a cerebrovascular disorder mostly observed in East Asian countries. It shows progressive stenosis and occlusion at internal carotid arteries, resulting in ischemia and cerebral infarction. Moreover, collateral vessels often rupture, resulting in patient death. We isolated mysterin gene, which was strongly associated with the onset of moyamoya disease; however, its function remained unknown. We recently succeeded in demonstrating that mysterin serves as a regulator of lipid metabolism with tissue culture cell system, for the first time.
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