| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Photosystem II (PSII) is susceptible to inactivation under strong light, and this phenomenon is referred to as photoinhibition of PSII. In the present study, we found that oxidation of translation factor EF-Tu is associated with photoinhibition of PSII in cyanobacterium Synechocystis sp. PCC 6803. Under strong light, reactive oxygen species, which are generated from the photosynthetic machinery, oxidize a specific cysteine residue of EF-Tu and inactivate its function, resulting in the suppression of protein synthesis and inhibition of the repair of PSII. When photosynthetic cells acclimate to strong light, PSII becomes more resistant to photoinhibtion. We found that increased levels of EF-Tu play an important role in the acclimation of PSII to strong light, by protecting protein synthesis from oxidative stress and by enhancing the repair of PSII.
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