| Project/Area Number |
15K07125
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Morphology/Structure
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| Research Institution | Shizuoka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MUKUDA Takao 鳥取大学, 医学部, 講師 (60346335)
KITANO Jun 国立遺伝学研究所, 集団遺伝研究系, 教授 (80346105)
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| Research Collaborator |
RAVINET Mark University of Oslo, Centre for Ecological and Evolutionary Synthesis, Researcher
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | リラキシン / イトヨ / 脳 / 量的形質遺伝子座解析 / 浸透圧調節 / QTL解析 / リラキシン受容体 / 血漿ナトリウム値 / 環境浸透圧 / 量的形質遺伝子座 / 遺伝的分化 / 神経ペプチド / lateral lemniscus / griseum centrale |
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| Outline of Final Research Achievements |
Relaxin is known as a hormone that has roles to help pregnancy and childbirth. The existence of relaxin gene has been confirmed in all vertebrates including fish. However, the functions of relaxin other than mammals are not well understood. Therefore, the function of relaxin was analyzed and the physiological significance of relaxin of teleosts was examined upon the perspective of comparative endocrinology and evolution. The sites of expression of the relaxin genes in the brain of stickleback were histologically analyzed. In order to clarify the regulatory mechanism of relaxin expression in the brain, expression mechanism of relaxin gene was analyzed by quantitative trait locus method.
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