| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
In the breeding season, sexually developed male newt vibrates its tail in front of the female partner at an early stage of courtship behavior. This behavior is elicited by several hormonal factors such as prolactin and arginine vasotocin (AVT), and androgen. However, the mechanism of the regulation of courtship behavior by these hormones is still unkonwn. In this study, we have obtained following results: 1) It was revealed that androgen up-regulates the expression of AVT precursor gene in the preoptic area of the brain of male newt. 2) It was confirmed that the expression of four-types of AVT receptors in the newt brain, including V2b-type receptor, which is identified as a novel AVT receptor subtype. 3) It was revealed that the numbers of phospho-ERK1/2-immunoreactive cells increased in the medial pallium and bed nucleus of the stria terminalis in the telencephalon, preoptic area and ventral and dorsal hypothalamic nuclei in the diencephalon during courtship behavior.
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